Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15276910 | 0.91 | HTR2B (0.56) | LMNARAB9AALDH1A1MAPTTSHR | |
| SCHEMBL21844860 | 0.90 | SMN1; SMN2 (0.58) | LMNARAB9AALDH1A1MAPTTSHR | |
| SCHEMBL15276906 | 0.86 | SIRT2 (0.52) | LMNARAB9AALDH1A1MAPTTSHR | |
| SCHEMBL15276904 | 0.85 | MAPT (0.52) | LMNARAB9AALDH1A1MAPTTSHR | |
| SCHEMBL19157167 | 0.84 | LMNA (0.54) | LMNARAB9AALDH1A1MAPTTSHR | |
| SCHEMBL15276907 | 0.84 | SLC6A9 (0.46) | LMNARAB9AALDH1A1MAPTTSHR | |
| SCHEMBL15276908 | 0.83 | ALDH1A1 (0.44) | LMNARAB9AALDH1A1MAPTTSHR | |
| SCHEMBL15276909 | 0.83 | RAB9A (0.50) | LMNARAB9AALDH1A1MAPTTSHR | |
| SCHEMBL21844861 | 0.79 | PSEN1 (0.38) | ALDH1A1MAPTGAASMN1; SMN2KMT2A | |
| SCHEMBL20084043 | 0.77 | SMN1; SMN2 (0.47) | LMNARAB9AALDH1A1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3312160-B1 | HEPATITIS B ANTIVIRAL AGENTS | NOVIRA THERAPEUTICS INC (US) | 2020-03-18 | — | — | EP | disclosed |
| EP-3312160-A1 | HEPATITIS B ANTIVIRAL AGENTS | Novira Therapeutics Inc. (US) | 2018-04-25 | — | — | EP | disclosed |