SCHEMBL20090199

SCHEMBL20090199

O=P(c1ccccc1)(c1ccc(-c2ccc3nc4c5c6ccccc6ccc5c5ccc(-c6cnc7cc(P(=O)(c8ccc9ccccc9c8)c8ccc9ccccc9c8)ccc7c6)cc5n4c3c2)nc1)c1ccc2ccccc2c1

nearest known ligand 0.31

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FTO Q9C0B1 1/20 0.31
EGLN1 Q9GZT9 1/20 0.31
EGLN3 Q9H6Z9 1/20 0.31
PIK3CD O00329 1/20 0.30
PIK3CB P42338 1/20 0.30
MTOR P42345 1/20 0.30
PIK3CG P48736 1/20 0.30
CYP11B1 P15538 1/20 0.30
CYP11B2 P19099 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20090191 0.98 MTOR (0.31) FTOEGLN1EGLN3PIK3CDPIK3CB
SCHEMBL20096407 0.95
SCHEMBL20096638 0.94
SCHEMBL20090184 0.92 MTOR (0.31) FTOEGLN1EGLN3PIK3CDPIK3CB
SCHEMBL20090250 0.89 PIK3CD (0.32) PIK3CDPIK3CBMTORPIK3CG
SCHEMBL20090109 0.89 PTGES (0.33) CYP11B1CYP11B2
SCHEMBL20096352 0.88
SCHEMBL20090193 0.88 UTRN (0.32)
SCHEMBL20090254 0.87 CYP11B1 (0.32) CYP11B1CYP11B2
SCHEMBL19929008 0.87 ALDH1A1 (0.36) CYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10355225-B2 Heterocyclic compound and organic light emitting element comprising same LG CHEM, LTD. (KR) 2019-07-16 US disclosed
US-20180114923-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2018-04-26 US disclosed
US-20180114923-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2018-04-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180114923-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME CRY1, CRY2, PER2 FTO 391/4885EGLN1 3375/4885EGLN3 4000/4885
US-10355225-B2 Heterocyclic compound and organic light emitting element comprising same CRY1, CRY2, PER2 FTO 391/4885EGLN1 3375/4885EGLN3 4000/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.