SCHEMBL20090191

SCHEMBL20090191

O=P(c1ccccc1)(c1ccccc1)c1ccc(-c2ccc3nc4c5c6ccccc6ccc5c5ccc(-c6cnc7cc(P(=O)(c8ccccc8)c8ccccc8)ccc7c6)cc5n4c3c2)nc1

nearest known ligand 0.31

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MTOR P42345 2/20 0.31
PIK3CD O00329 1/20 0.31
PIK3CA P42336 1/20 0.31
PIK3CB P42338 1/20 0.31
PIK3CG P48736 1/20 0.31
PTGES O14684 1/20 0.31
METAP2 P50579 1/20 0.31
FTO Q9C0B1 1/20 0.30
EGLN1 Q9GZT9 1/20 0.30
EGLN3 Q9H6Z9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20090199 0.98 FTO (0.31) MTORPIK3CDPIK3CBPIK3CGFTO
SCHEMBL20096407 0.96
SCHEMBL20096638 0.95
SCHEMBL20090184 0.94 MTOR (0.31) MTORPIK3CDPIK3CAPIK3CBPIK3CG
SCHEMBL20090250 0.90 PIK3CD (0.32) MTORPIK3CDPIK3CAPIK3CBPIK3CG
SCHEMBL20096352 0.89
SCHEMBL20090109 0.88 PTGES (0.33) PTGES
SCHEMBL19929008 0.88 ALDH1A1 (0.36) PTGES
SCHEMBL20096358 0.87 PTGES (0.31) PTGES
SCHEMBL20096520 0.87 PDGFRB (0.32) PIK3CDPIK3CA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10355225-B2 Heterocyclic compound and organic light emitting element comprising same LG CHEM, LTD. (KR) 2019-07-16 US disclosed
US-20180114923-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2018-04-26 US disclosed
US-20180114923-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2018-04-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180114923-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME CRY1, CRY2, PER2 MTOR 1571/4885PIK3CD 4347/4885PIK3CA 4430/4885
US-10355225-B2 Heterocyclic compound and organic light emitting element comprising same CRY1, CRY2, PER2 MTOR 1571/4885PIK3CD 4347/4885PIK3CA 4430/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.