SCHEMBL2009408

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2006926	0.91	HSD11B1 (0.58)	HSD11B1MEN1KMT2ATDP1POLB
	SCHEMBL2012534	0.90	HSD11B1 (0.59)	HSD11B1MEN1KMT2ATDP1POLB
	SCHEMBL13270639	0.90	KMT2A (0.48)	HSD11B1MEN1KMT2ATDP1POLB
	SCHEMBL2007289	0.89	MEN1 (0.47)	HSD11B1MEN1KMT2AMAPTPOLB
	SCHEMBL2006592	0.89	MEN1 (0.47)	HSD11B1MEN1KMT2AMAPTPOLB
	SCHEMBL2006326	0.87	ALDH1A1 (0.50)	POLBLMNALSSKDM4EALDH1A1
	SCHEMBL2008626	0.86	ALDH1A1 (0.60)	HSD11B1MEN1KMT2ATDP1POLB
	SCHEMBL4684441	0.86	ALDH1A1 (0.47)	HSD11B1MEN1KMT2ATDP1MAPT
	SCHEMBL3013840	0.83	HSD11B1 (0.58)	HSD11B1MEN1KMT2ATDP1MAPT
	SCHEMBL2006521	0.82	PKM (0.49)	HSD11B1MEN1KMT2AMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.