Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9660794 | 0.81 | F10 (0.39) | ALDH1A1POLBLMNAHSD17B10MAPK1 | |
| SCHEMBL5116398 | 0.80 | ALOX15 (0.42) | ALDH1A1POLBLMNAHSD17B10MAPK1 | |
| SCHEMBL18346711 | 0.80 | ALOX15 (0.42) | ALDH1A1POLBLMNAHSD17B10MAPK1 | |
| SCHEMBL5079218 | 0.79 | ATM (0.38) | ALDH1A1POLBLMNAHSD17B10MAPK1 | |
| SCHEMBL1964683 | 0.78 | ALDH1A1 (0.39) | ALDH1A1POLBLMNAHSD17B10MAPK1 | |
| SCHEMBL11179315 | 0.77 | ALDH1A1 (0.37) | ALDH1A1POLBLMNAHSD17B10MAPK1 | |
| SCHEMBL17444931 | 0.77 | BRD4 (0.40) | ALDH1A1POLBLMNAHSD17B10ATM | |
| SCHEMBL13640434 | 0.77 | BRD4 (0.40) | ALDH1A1POLBLMNAHSD17B10ATM | |
| SCHEMBL15325943 | 0.77 | ALDH1A1 (0.37) | ALDH1A1POLBLMNAHSD17B10MAPK1 | |
| SCHEMBL29192006 | 0.77 | ALDH1A1 (0.37) | ALDH1A1POLBLMNAHSD17B10ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190248746-A1 | CYCLOPROPYL UNSATURATED QUINOLINE COMPOUND USED AS LEUKOTRIENE RECEPTOR ANTAGONIST AND APPLICATIONS THEREOF | GUANGDONG MOLTECH PHARMA CO LTD (CN) | 2019-08-15 | — | — | US | disclosed |
| US-10315997-B2 | Cyclopropyl unsaturated quinoline compound used as leukotriene receptor antagonist and applications thereof | GUANGDONG MOLTECH PHARMA CO., LTD. (CN) | 2019-06-11 | — | — | US | disclosed |
| US-20180118687-A1 | CYCLOPROPYL UNSATURATED QUINOLINE COMPOUND USED AS LEUKOTRIENE RECEPTOR ANTAGONIST AND APPLICATIONS THEREOF | GUANGDONG MOLTECH PHARMA CO., LTD. (CN) | 2018-05-03 | — | — | US | disclosed |
| US-20180118687-A1 | CYCLOPROPYL UNSATURATED QUINOLINE COMPOUND USED AS LEUKOTRIENE RECEPTOR ANTAGONIST AND APPLICATIONS THEREOF | GUANGDONG MOLTECH PHARMA CO., LTD. (CN) | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190248746-A1 | CYCLOPROPYL UNSATURATED QUINOLINE COMPOUND USED AS LEUKOTRIENE RECEPTOR ANTAGONIST AND APPLICATIONS THEREOF | LTC4S, LTB4R, CYSLTR1 | ALDH1A1 1624/4885POLB 3501/4885LMNA 613/4885 |
| US-20180118687-A1 | CYCLOPROPYL UNSATURATED QUINOLINE COMPOUND USED AS LEUKOTRIENE RECEPTOR ANTAGONIST AND APPLICATIONS THEREOF | LTC4S, LTB4R, CYSLTR1 | ALDH1A1 1566/4885POLB 3551/4885LMNA 703/4885 |
| US-10315997-B2 | Cyclopropyl unsaturated quinoline compound used as leukotriene receptor antagonist and applications thereof | LTC4S, LTB4R, CYSLTR1 | ALDH1A1 1566/4885POLB 3551/4885LMNA 703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.