Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25923931 | 0.85 | HTR4 (0.33) | KDM1A | |
| SCHEMBL21088950 | 0.81 | DRD2 (0.31) | KDM1A | |
| SCHEMBL25923922 | 0.80 | — | — | |
| SCHEMBL25924094 | 0.80 | OPRM1 (0.30) | — | |
| SCHEMBL21349212 | 0.78 | KDM1A (0.39) | KDM1A | |
| SCHEMBL25923913 | 0.78 | KDM1A (0.33) | KDM1A | |
| SCHEMBL20106792 | 0.75 | KDM1A (0.44) | KDM1A | |
| SCHEMBL25923917 | 0.74 | ALDH1A1 (0.32) | — | |
| SCHEMBL21089313 | 0.72 | EPHX2 (0.35) | KDM1A | |
| SCHEMBL25923845 | 0.71 | ALOX15 (0.33) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3532459-B1 | LSD1 INHIBITORS AND MEDICAL USES THEREOF | CONSTELLATION PHARMACEUTICALS INC (US) | 2023-08-02 | — | — | EP | disclosed |
| WO-2018081343-A1 | LSD1 INHIBITORS AND MEDICAL USES THEREOF | CONSTELLATION PHARMACEUTICALS, INC. (US) | 2018-05-03 | — | — | WO | disclosed |