SCHEMBL2010738

SCHEMBL2010738

CCOc1c(C)cc(C)c(C(=O)[PH](=O)c2ccccc2)c1C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.36
KDM4E B2RXH2 4/20 0.36
ALDH1A1 P00352 4/20 0.36
HPGD P15428 4/20 0.36
GAA P10253 3/20 0.36
GLA P06280 2/20 0.36
HSD17B10 Q99714 2/20 0.36
TSHR P16473 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.34
ADORA3 P0DMS8 2/20 0.34
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
NFKB1 P19838 1/20 0.33
NFKB2 Q00653 1/20 0.33
RELA Q04206 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
LMNA P02545 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13720820 0.80 LMNA (0.32) MAPTKDM4EADORA3RAB9ALMNA
SCHEMBL13836775 0.77 ALDH1A1 (0.35) MAPTKDM4EALDH1A1HPGDGAA
SCHEMBL15552696 0.76 ALDH1A1 (0.39) MAPTALDH1A1HPGDGAAHSD17B10
SCHEMBL82366 0.74 LMNA (0.40) KDM4EALDH1A1HPGDGAAL3MBTL1
SCHEMBL27947927 0.74 CES2 (0.33) MAPTALDH1A1HPGDTSHRL3MBTL1
SCHEMBL10482130 0.72 KMT2A (0.41) MAPTKDM4EALDH1A1HPGDGLA
SCHEMBL1024553 0.72 LMNA (0.39) KDM4EALDH1A1HPGDGAAL3MBTL1
SCHEMBL1024427 0.72 LMNA (0.39) KDM4EALDH1A1HPGDGAAL3MBTL1
SCHEMBL21831853 0.72 LMNA (0.39) KDM4EALDH1A1HPGDGAAL3MBTL1
Potassium SCHEMBL29629366 0.72 LMNA (0.39) KDM4EALDH1A1HPGDGAAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140220315-A1 HIGH-STRETCH ENERGY CURABLE INKS & METHOD OF USE IN HEAT TRANSFER LABEL APPLICATIONS SUN CHEMICAL CORPORATION (US) 2014-08-07 US claimed
EP-3700975-B1 ACTINICALLY CURABLE ADHESIVE COMPOSITION WITH IMPROVED PROPERTIES SUN CHEMICAL CORP (US) 2023-12-06 EP disclosed
US-11180681-B2 Actinically curable adhesive composition with improved properties SUN CHEMICAL CORPORATION (US) 2021-11-23 US disclosed
US-20200339838-A1 ACTINICALLY CURABLE ADHESIVE COMPOSITION WITH IMPROVED PROPERTIES SUN CHEMICAL CORPORATION (US) 2020-10-29 US disclosed
EP-3700975-A1 ACTINICALLY CURABLE ADHESIVE COMPOSITION WITH IMPROVED PROPERTIES Sun Chemical Corporation (US) 2020-09-02 EP disclosed
US-9275560-B2 High-stretch energy curable inks and method of use in heat transfer label applications SUN CHEMICAL CORPORATION (US) 2016-03-01 US disclosed
US-20140220315-A1 HIGH-STRETCH ENERGY CURABLE INKS & METHOD OF USE IN HEAT TRANSFER LABEL APPLICATIONS SUN CHEMICAL CORPORATION (US) 2014-08-07 US disclosed
US-7963124-B2 Fiber cure with extended irradiators CORNING INCORPORATED (US) 2011-06-21 US disclosed