SCHEMBL1024427

SCHEMBL1024427

Cc1cc(C)c(C(=O)[PH](=O)c2ccccc2)c(C)c1.[NaH]

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.39
KDM4E B2RXH2 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
KMT2A Q03164 3/20 0.37
MEN1 O00255 2/20 0.35
METAP2 P50579 1/20 0.35
HPGD P15428 2/20 0.34
FFAR4 Q5NUL3 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
MCOLN3 Q8TDD5 1/20 0.34
GAA P10253 1/20 0.34
NFE2L2 Q16236 1/20 0.33
ALDH1A1 P00352 1/20 0.33
CRHR1 P34998 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21831853 1.00 LMNA (0.39) LMNAKDM4EL3MBTL1KMT2AMEN1
SCHEMBL82366 0.98 LMNA (0.40) LMNAKDM4EL3MBTL1KMT2AMEN1
SCHEMBL29365769 0.97 LMNA (0.39) LMNAKDM4EL3MBTL1KMT2AMEN1
Lithium SCHEMBL29779115 0.97 LMNA (0.39) LMNAKDM4EL3MBTL1KMT2AMEN1
SCHEMBL28781832 0.97 LMNA (0.39) LMNAKDM4EL3MBTL1KMT2AMEN1
SCHEMBL1024553 0.97 LMNA (0.39) LMNAKDM4EL3MBTL1KMT2AMEN1
Potassium SCHEMBL29629366 0.97 LMNA (0.39) LMNAKDM4EL3MBTL1KMT2AMEN1
Ammonia Solution, Strong SCHEMBL2909570 0.97 LMNA (0.39) LMNAKDM4EL3MBTL1KMT2AMEN1
SCHEMBL28100158 0.97 LMNA (0.39) LMNAKDM4EL3MBTL1KMT2AMEN1
Benzophenone SCHEMBL28167644 0.91 ALDH1A1 (0.42) LMNAL3MBTL1KMT2AMEN1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 165 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12030970-B2 Curable composition and stereolithographic resin composition comprising same KURARAY CO., LTD. (JP) 2024-07-09 US disclosed
CN-114072439-B Curable composition and resin composition for photofabrication comprising same 株式会社可乐丽 2024-05-14 CN disclosed
WO-2024096019-A1 DENTAL ADHESIVE COMPOSITION クラレノリタケデンタル株式会社 2024-05-10 WO disclosed
CN-113993497-B Curable composition and resin composition for photofabrication comprising same 株式会社可乐丽 2024-03-22 CN disclosed
WO-2024053223-A1 CARIOUS TOOTH STRUCTURE RECOVERY AGENT, AND DENTAL ADHESIVE KIT クラレノリタケデンタル株式会社 2024-03-14 WO disclosed
US-20240074945-A1 CURABLE COMPOSITION FOR DENTAL RESTORATION KURARAY NORITAKE DENTAL INC. (JP) 2024-03-07 US disclosed
CN-112752776-B Resin composition for photofabrication 可乐丽则武齿科株式会社 2024-02-09 CN disclosed
EP-2979679-B1 CURABLE COMPOSITION FOR DENTAL USE KURARAY NORITAKE DENTAL INC (JP) 2023-11-29 EP disclosed
US-11814454-B2 Curable composition, and resin composition for stereolithography prepared therefrom KURARAY CO., LTD. (JP) 2023-11-14 US disclosed
EP-4268792-A1 ADHESIVE COMPOSITION FOR PHOTOFABRICATION ARTICLES Kuraray Noritake Dental Inc. (JP) 2023-11-01 EP disclosed
CN-101595139-A Polymerizable monomer-containing composition KURARAY MEDICAL INC (JP) 2009-12-02 CN disclosed
CN-101589070-A Composition and dental material KURARAY MEDICAL INC (JP) 2009-11-25 CN disclosed
EP-2112178-A1 POLYMERIZABLE MONOMER-CONTAINING COMPOSITION Kuraray Medical Inc. (JP) 2009-10-28 EP disclosed
EP-2112177-A1 POLYMERIZABLE MONOMER-CONTAINING COMPOSITION Kuraray Medical Inc. (JP) 2009-10-28 EP disclosed
EP-2108663-A1 POLYMERIZABLE MONOMER, POLYMERIZABLE COMPOSITION AND DENTAL MATERIAL Kuraray Medical Inc. (JP) 2009-10-14 EP disclosed
EP-2108664-A1 COMPOSITION AND DENTAL MATERIAL Kuraray Medical Inc. (JP) 2009-10-14 EP disclosed
CN-101547930-A Novel compound, composition containing same, and method for producing polymerizable amide KURARAY MEDICAL INC (JP) 2009-09-30 CN disclosed
EP-2070935-A1 NOVEL COMPOUND, COMPOSITION COMPRISING THE SAME, AND PROCESS FOR PRODUCTION OF POLYMERIZABLE AMIDE Kuraray Medical Inc. (JP) 2009-06-17 EP disclosed
US-20090105361-A1 Camphorquinone Derivative Having Acylphosphine Oxide Group, Photopolymerization Catalyst And Photo/Chemical Polymerization Catalyst Containing The Same And Hardenable Composition Contaning The Same KABUSHIKI KAISHA SHOFU 2009-04-23 US disclosed
US-20090048426-A1 POLYMERIZABLE PHOSPHONIC ACID DERIVATIVE AND ADHESIVE COMPOSITION COMPRISING THE SAME KABUSHIKI KAISHA SHOFU (JP) 2009-02-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11814454-B2 Curable composition, and resin composition for stereolithography prepared therefrom WASF2, COPE, ARCN1 LMNA 2226/4885KDM4E 2578/4885L3MBTL1 3917/4885
US-20090105361-A1 Camphorquinone Derivative Having Acylphosphine Oxide Group, Photopolymerization Catalyst And Photo/Chemical Polymerization Catalyst Containing The Same And Hardenable Composition Contaning The Same POLQ, GAK, CAD LMNA 1473/4885KDM4E 1447/4885L3MBTL1 4765/4885
US-12030970-B2 Curable composition and stereolithographic resin composition comprising same ARL1, ASH2L, VCL LMNA 2664/4885KDM4E 915/4885L3MBTL1 1735/4885
US-20240074945-A1 CURABLE COMPOSITION FOR DENTAL RESTORATION SMCHD1, WDR26, KAT6A LMNA 2183/4885KDM4E 176/4885L3MBTL1 2258/4885
US-20090048426-A1 POLYMERIZABLE PHOSPHONIC ACID DERIVATIVE AND ADHESIVE COMPOSITION COMPRISING THE SAME PTK2, ITGA1, ACTN1 LMNA 3699/4885KDM4E 3960/4885L3MBTL1 2616/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.