SCHEMBL1024553

SCHEMBL1024553

Cc1cc(C)c(C(=O)[PH](=O)c2ccccc2)c(C)c1.[KH]

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.39
KDM4E B2RXH2 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
KMT2A Q03164 3/20 0.37
MEN1 O00255 2/20 0.35
METAP2 P50579 1/20 0.35
HPGD P15428 2/20 0.34
FFAR4 Q5NUL3 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
MCOLN3 Q8TDD5 1/20 0.34
GAA P10253 1/20 0.34
NFE2L2 Q16236 1/20 0.33
ALDH1A1 P00352 1/20 0.33
CRHR1 P34998 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL82366 0.98 LMNA (0.40) LMNAKDM4EL3MBTL1KMT2AMEN1
Potassium SCHEMBL29629366 0.97 LMNA (0.39) LMNAKDM4EL3MBTL1KMT2AMEN1
SCHEMBL28781832 0.97 LMNA (0.39) LMNAKDM4EL3MBTL1KMT2AMEN1
SCHEMBL28100158 0.97 LMNA (0.39) LMNAKDM4EL3MBTL1KMT2AMEN1
Ammonia Solution, Strong SCHEMBL2909570 0.97 LMNA (0.39) LMNAKDM4EL3MBTL1KMT2AMEN1
Lithium SCHEMBL29779115 0.97 LMNA (0.39) LMNAKDM4EL3MBTL1KMT2AMEN1
SCHEMBL1024427 0.97 LMNA (0.39) LMNAKDM4EL3MBTL1KMT2AMEN1
SCHEMBL29365769 0.97 LMNA (0.39) LMNAKDM4EL3MBTL1KMT2AMEN1
SCHEMBL21831853 0.97 LMNA (0.39) LMNAKDM4EL3MBTL1KMT2AMEN1
Benzophenone SCHEMBL28167644 0.91 ALDH1A1 (0.42) LMNAL3MBTL1KMT2AMEN1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112752776-B Resin composition for photofabrication 可乐丽则武齿科株式会社 2024-02-09 CN disclosed
EP-4268792-A1 ADHESIVE COMPOSITION FOR PHOTOFABRICATION ARTICLES Kuraray Noritake Dental Inc. (JP) 2023-11-01 EP disclosed
WO-2023190931-A1 RESIN COMPOSITION FOR STEREOLITHOGRAPHY クラレノリタケデンタル株式会社 2023-10-05 WO disclosed
CN-116669679-A Adhesive composition for photo-molded article 可乐丽则武齿科株式会社 2023-08-29 CN disclosed
WO-2023042913-A1 METHOD FOR PRODUCING DENTURE クラレノリタケデンタル株式会社 2023-03-23 WO disclosed
WO-2023042912-A1 METHOD FOR MANUFACTURING INTRAORAL APPLIANCE EQUIPPED WITH COATING, AND INTRAORAL APPLIANCE EQUIPPED WITH COATING クラレノリタケデンタル株式会社 2023-03-23 WO disclosed
WO-2023042915-A1 STEREOLITHOGRAPHY PLATE DENTURE MANUFACTURING KIT, AND METHOD FOR MANUFACTURING PLATE DENTURE クラレノリタケデンタル株式会社 2023-03-23 WO disclosed
CN-115038730-A Resin composition for stereolithography 可乐丽则武齿科株式会社 2022-09-09 CN disclosed
CN-114430750-A Resin composition for stereolithography 可乐丽则武齿科株式会社 2022-05-03 CN disclosed
CN-113906068-A Resin composition for stereolithography 可乐丽则武齿科株式会社 2022-01-07 CN disclosed
US-20100056665-A1 POLYMERIZABLE MONOMER, POLYMERIZABLE COMPOSITION AND DENTAL MATERIAL KURARAY MEDICAL INC. (JP) 2010-03-04 US disclosed
US-20100048761-A1 POLYMERIZABLE MONOMER-CONTAINING COMPOSITION KURARAY MEDICAL INC. (JP) 2010-02-25 US disclosed
US-20100048762-A1 COMPOSITION AND DENTAL MATERIAL KURARAY MEDICAL INC. (JP) 2010-02-25 US disclosed
US-20100036075-A1 POLYMERIZABLE MONOMER-CONTAINING COMPOSITION KURARAY MEDICAL INC. (JP) 2010-02-11 US disclosed
EP-2133368-A1 POLYMERIZABLE MONOMER, POLYMERIZABLE COMPOSITION AND DENTAL MATERIAL Kuraray Medical Inc. (JP) 2009-12-16 EP disclosed
EP-2112177-A1 POLYMERIZABLE MONOMER-CONTAINING COMPOSITION Kuraray Medical Inc. (JP) 2009-10-28 EP disclosed
EP-2112178-A1 POLYMERIZABLE MONOMER-CONTAINING COMPOSITION Kuraray Medical Inc. (JP) 2009-10-28 EP disclosed
EP-2108663-A1 POLYMERIZABLE MONOMER, POLYMERIZABLE COMPOSITION AND DENTAL MATERIAL Kuraray Medical Inc. (JP) 2009-10-14 EP disclosed
EP-2108664-A1 COMPOSITION AND DENTAL MATERIAL Kuraray Medical Inc. (JP) 2009-10-14 EP disclosed
US-20090105361-A1 Camphorquinone Derivative Having Acylphosphine Oxide Group, Photopolymerization Catalyst And Photo/Chemical Polymerization Catalyst Containing The Same And Hardenable Composition Contaning The Same KABUSHIKI KAISHA SHOFU 2009-04-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100048761-A1 POLYMERIZABLE MONOMER-CONTAINING COMPOSITION WDR82, PWWP2B, WDR5 LMNA 2227/4885KDM4E 2122/4885L3MBTL1 4408/4885
US-20100048762-A1 COMPOSITION AND DENTAL MATERIAL PHOSPHO1, PDS5B, ITGB5 LMNA 2758/4885KDM4E 2282/4885L3MBTL1 2923/4885
US-20090105361-A1 Camphorquinone Derivative Having Acylphosphine Oxide Group, Photopolymerization Catalyst And Photo/Chemical Polymerization Catalyst Containing The Same And Hardenable Composition Contaning The Same POLQ, GAK, CAD LMNA 1473/4885KDM4E 1447/4885L3MBTL1 4765/4885
US-20100056665-A1 POLYMERIZABLE MONOMER, POLYMERIZABLE COMPOSITION AND DENTAL MATERIAL ITGA1, COL1A1, MACF1 LMNA 1086/4885KDM4E 3332/4885L3MBTL1 4012/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.