Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CCR2 | P41597 | 2/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20108429 | 0.75 | TSHR (0.38) | PDK2RAPGEF4 | |
| SCHEMBL25844613 | 0.68 | AR (0.49) | — | |
| SCHEMBL24394081 | 0.66 | SLC6A3 (0.49) | HSD11B1OPRM1OPRL1 | |
| SCHEMBL8297897 | 0.65 | MAOB (0.40) | HSD11B1OPRM1OPRK1OPRL1 | |
| SCHEMBL13197431 | 0.64 | SLC6A3 (0.51) | HSD11B1OPRM1OPRL1 | |
| SCHEMBL22031352 | 0.64 | PDK2 (0.48) | PDK2HSD11B1RAPGEF4 | |
| SCHEMBL22686809 | 0.64 | RAB9A (0.36) | HSD11B1HTT | |
| SCHEMBL436499 | 0.64 | SLC6A4 (0.46) | HSD11B1CCR2OPRK1 | |
| SCHEMBL20108386 | 0.64 | AR (0.45) | PDK2HSD11B1RAPGEF4 | |
| SCHEMBL18272233 | 0.63 | SMN1; SMN2 (0.40) | RAPGEF4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2964635-B1 | ANTIVIRAL COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2018-05-02 | — | — | EP | disclosed |