SCHEMBL20109429

SCHEMBL20109429

Cc1ccc(N(c2ccc(C)cc2)c2ccc(/C=C/c3ccc(N(C=C(c4ccccc4)c4ccccc4)c4ccccc4)cc3)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TRPM8 Q7Z2W7 2/20 0.44
MAPT P10636 2/20 0.44
ALDH1A1 P00352 1/20 0.44
CYP3A4 P08684 1/20 0.44
HPGD P15428 1/20 0.44
RELA Q04206 1/20 0.40
PTGS2 P35354 2/20 0.39
CTDSP1 Q9GZU7 1/20 0.39
APP P05067 1/20 0.39
CYP1B1 Q16678 1/20 0.38
FGF23 Q9GZV9 1/20 0.37
NFE2L2 Q16236 2/20 0.36
EGFR P00533 1/20 0.36
SNCA P37840 1/20 0.35
ALOX5 P09917 1/20 0.35
PTGS1 P23219 1/20 0.35
CES2 O00748 1/20 0.34
CES1 P23141 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13242001 0.99 MAPT (0.45) TRPM8MAPTALDH1A1CYP3A4HPGD
SCHEMBL15893566 0.92 TRPM8 (0.39) TRPM8MAPTALDH1A1CYP3A4HPGD
SCHEMBL17486890 0.88 ALDH1A1 (0.46) TRPM8MAPTALDH1A1CYP3A4HPGD
SCHEMBL13609992 0.88 ALDH1A1 (0.46) TRPM8MAPTALDH1A1CYP3A4HPGD
SCHEMBL13986161 0.87 NFE2L2 (0.45) TRPM8MAPTALDH1A1CYP3A4HPGD
SCHEMBL13163966 0.86 RELA (0.48) TRPM8MAPTRELACTDSP1CYP1B1
SCHEMBL13909669 0.86 RELA (0.48) TRPM8MAPTRELACTDSP1CYP1B1
SCHEMBL4367692 0.86 CES2 (0.44) TRPM8MAPTALDH1A1CYP3A4HPGD
SCHEMBL14256375 0.85 PTGS2 (0.54) TRPM8MAPTALDH1A1CYP3A4HPGD
SCHEMBL16807030 0.85 TRPM8 (0.42) TRPM8MAPTALDH1A1CYP3A4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10012916-B2 Photoreceptor for electrophotography, and photoreceptor cartridge and image forming apparatus employing the same S-PRINTING SOLUTION CO., LTD. (KR) 2018-07-03 US disclosed
US-10012916-B2 Photoreceptor for electrophotography, and photoreceptor cartridge and image forming apparatus employing the same S-PRINTING SOLUTION CO., LTD. (KR) 2018-07-03 US disclosed
US-20180120716-A1 PHOTORECEPTOR FOR ELECTROPHOTOGRAPHY, AND PHOTORECEPTOR CARTRIDGE AND IMAGE FORMING APPARATUS EMPLOYING THE SAME S-PRINTING SOLUTION CO., LTD. (KR) 2018-05-03 US disclosed
US-20180120716-A1 PHOTORECEPTOR FOR ELECTROPHOTOGRAPHY, AND PHOTORECEPTOR CARTRIDGE AND IMAGE FORMING APPARATUS EMPLOYING THE SAME S-PRINTING SOLUTION CO., LTD. (KR) 2018-05-03 US disclosed