Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.36 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.36 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | TYMS | P04818 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3744088 | 0.77 | CA1 (0.42) | CA1CA2CA7CA9SMARCA2 | |
| SCHEMBL10784839 | 0.73 | SMARCA2 (0.37) | CA1CA2CA7CA9SMARCA2 | |
| SCHEMBL2044047 | 0.68 | MAOB (0.36) | CA1CA2CA7CA9CYP19A1 | |
| SCHEMBL868796 | 0.67 | ALDH1A1 (0.53) | CA1CA2CA9MEN1NPC1 | |
| SCHEMBL11255003 | 0.65 | NPC1 (0.42) | MAPK1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL30286685 | 0.64 | MAOB (0.40) | CA1CA2CA7CA9MEN1 | |
| SCHEMBL11808470 | 0.63 | PBRM1 (0.55) | CA1CA2CA7CA9SMARCA2 | |
| SCHEMBL10716838 | 0.63 | MAOA (0.52) | CA1CA2CA7CA9SMARCA2 | |
| SCHEMBL5866470 | 0.63 | CA1 (0.52) | CA1CA2CA7CA9SMARCA2 | |
| SCHEMBL13487412 | 0.63 | CA1 (0.52) | CA1CA2CA7CA9MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10662168-B2 | Compounds for treating parasitic infections | UNIVERSITY OF MARYLAND, COLLEGE PARK (US) | 2020-05-26 | — | — | US | disclosed |
| US-20190152938-A1 | COMPOUNDS FOR TREATING PARASITIC INFECTIONS | UNIVERSITY OF MARYLAND, COLLEGE PARK | 2019-05-23 | — | — | US | disclosed |
| US-10227320-B2 | Compounds for treating parasitic infections | UNIVERSITY OF MARYLAND, COLLEGE PARK (US) | 2019-03-12 | — | — | US | disclosed |
| US-20180118704-A1 | COMPOUNDS FOR TREATING PARASITIC INFECTIONS | UNIVERSITY OF MARYLAND, COLLEGE PARK | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190152938-A1 | COMPOUNDS FOR TREATING PARASITIC INFECTIONS | CYC1, COX15, SLC40A1 | CA1 4655/4885CA2 1926/4885CA7 2919/4885 |
| US-20180118704-A1 | COMPOUNDS FOR TREATING PARASITIC INFECTIONS | CYC1, COX15, SLC40A1 | CA1 4655/4885CA2 1926/4885CA7 2919/4885 |
| US-10662168-B2 | Compounds for treating parasitic infections | CYC1, COX15, SLC40A1 | CA1 4655/4885CA2 1926/4885CA7 2919/4885 |
| US-10227320-B2 | Compounds for treating parasitic infections | CYC1, COX15, SLC40A1 | CA1 4655/4885CA2 1926/4885CA7 2919/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.