Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | PSMG3 | Q9BT73 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.31 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20110959 | 0.88 | PSMG3 (0.33) | PSMG3 | |
| SCHEMBL13134484 | 0.71 | LMNA (0.42) | POLB | |
| SCHEMBL9507056 | 0.69 | LMNA (0.44) | POLB | |
| SCHEMBL20110957 | 0.67 | CYP3A4 (0.32) | — | |
| SCHEMBL12157049 | 0.65 | PSMG3 (0.49) | POLBPSMG3 | |
| SCHEMBL5865884 | 0.64 | LMNA (0.44) | POLB | |
| SCHEMBL28659567 | 0.63 | POLB (0.57) | POLBPSMG3 | |
| SCHEMBL6768198 | 0.63 | ABCB11 (0.36) | POLBABCB11PDE4APDE4BPDE4C | |
| SCHEMBL12157050 | 0.62 | SMN1; SMN2 (0.46) | POLBPSMG3 | |
| SCHEMBL14580035 | 0.62 | POLB (0.44) | POLBABCB11PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180118674-A1 | HYDROGEN SULFIDE PRECURSORS AND CONJUGATES THEREOF | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC (US) | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180118674-A1 | HYDROGEN SULFIDE PRECURSORS AND CONJUGATES THEREOF | CBS, TST, STS | POLB 4251/4885ABCB11 2669/4885PDE4A 4503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.