SCHEMBL20111324

SCHEMBL20111324

CCc1ccc2c(c1F)-c1c-2ccc(F)c1F

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 16/20 0.37
PTGS1 P23219 6/20 0.35
RIPK1 Q13546 1/20 0.35
FEN1 P39748 1/20 0.34
P2RX7 Q99572 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20111216 0.84 CTSL (0.39) PTGS2PTGS1RIPK1FEN1
SCHEMBL1547626 0.80 RIPK1 (0.47) RIPK1P2RX7
SCHEMBL20117594 0.77 NQO1 (0.35) FEN1
SCHEMBL15471665 0.75 CTSS (0.42) RIPK1FEN1
SCHEMBL20102397 0.74 CTSL (0.39) FEN1
SCHEMBL19196278 0.74 GABRA1 (0.39) RIPK1FEN1P2RX7
SCHEMBL20169915 0.72 CTSS (0.42) RIPK1
SCHEMBL16933827 0.72 HEXA (0.40) PTGS2PTGS1P2RX7
SCHEMBL19193286 0.71 RIPK1 (0.38) RIPK1FEN1P2RX7
SCHEMBL8097082 0.71 RIPK1 (0.38) RIPK1P2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10323187-B2 Liquid crystal compound having biphenylene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2019-06-18 US disclosed
US-20180119009-A1 LIQUID CRYSTAL COMPOUND HAVING BIPHENYLENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180119009-A1 LIQUID CRYSTAL COMPOUND HAVING BIPHENYLENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE YBX1, PIEZO1, C1S PTGS2 4062/4885PTGS1 3924/4885RIPK1 1596/4885
US-10323187-B2 Liquid crystal compound having biphenylene, liquid crystal composition and liquid crystal display device YBX1, PIEZO1, C1S PTGS2 4062/4885PTGS1 3924/4885RIPK1 1596/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.