SCHEMBL20114602

SCHEMBL20114602

C=C(Cc1ccc2c3ccccc3c3ccccc3c2c1)c1ccc(Br)cc1-c1ccccc1C

nearest known ligand 0.32

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PTGES O14684 1/20 0.32
BACE1 P56817 1/20 0.32
HPGD P15428 2/20 0.32
ALDH1A1 P00352 2/20 0.32
KDM4E B2RXH2 1/20 0.32
USP2 O75604 1/20 0.32
HSD17B10 Q99714 1/20 0.32
KMT2A Q03164 2/20 0.32
MEN1 O00255 1/20 0.32
RXFP1 Q9HBX9 1/20 0.32
EGFR P00533 1/20 0.30
FFAR1 O14842 1/20 0.30
TACR1 P25103 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20114159 0.87 CYP1A2 (0.40) HPGDALDH1A1KDM4EKMT2AMEN1
SCHEMBL20114138 0.86 ALDH1A1 (0.36) HPGDALDH1A1KDM4EKMT2AMEN1
SCHEMBL20114041 0.84 ALDH1A1 (0.38) ALDH1A1KMT2AMEN1FFAR1
SCHEMBL20114097 0.82 HTR7 (0.42) BACE1ALDH1A1FFAR1
SCHEMBL20114149 0.81 PDK2 (0.32)
SCHEMBL20114229 0.77
SCHEMBL20114136 0.74 ALOX5 (0.39) HPGDALDH1A1KDM4EUSP2HSD17B10
SCHEMBL20114086 0.74 ADORA2A (0.37) HPGDALDH1A1KDM4EKMT2AMEN1
SCHEMBL20114168 0.68 ALOX5 (0.41) HPGDALDH1A1KDM4EUSP2HSD17B10
SCHEMBL21425499 0.68 PLA2G10 (0.41) HPGDALDH1A1KDM4EHSD17B10TACR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018080067-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING SAME 주식회사 두산 2018-05-03 WO disclosed