SCHEMBL20114138

SCHEMBL20114138

C=C(Cc1ccccc1)c1ccc(Br)cc1-c1ccccc1C

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.36
ALDH2 P05091 2/20 0.36
ALDH3A1 P30838 2/20 0.36
KMT2A Q03164 4/20 0.36
HPGD P15428 2/20 0.36
HTR7 P34969 2/20 0.35
PPARG P37231 1/20 0.35
PPARA Q07869 1/20 0.35
MEN1 O00255 3/20 0.35
SMN1; SMN2 Q16637 2/20 0.34
GAA P10253 1/20 0.34
FNTA P49354 1/20 0.33
FNTB P49356 1/20 0.33
TMEM97 Q5BJF2 1/20 0.33
SIGMAR1 Q99720 1/20 0.33
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20114041 0.92 ALDH1A1 (0.38) ALDH1A1KMT2AHTR7PPARGMEN1
SCHEMBL20114097 0.90 HTR7 (0.42) ALDH1A1ALDH2ALDH3A1HTR7
SCHEMBL20114602 0.86 PTGES (0.32) ALDH1A1KMT2AHPGDMEN1KDM4E
SCHEMBL20114149 0.81 PDK2 (0.32)
SCHEMBL20114159 0.80 CYP1A2 (0.40) ALDH1A1KMT2AHPGDMEN1SMN1; SMN2
SCHEMBL20114086 0.76 ADORA2A (0.37) ALDH1A1KMT2AHPGDMEN1KDM4E
SCHEMBL20114136 0.75 ALOX5 (0.39) ALDH1A1KMT2AHPGDMEN1KDM4E
SCHEMBL20114078 0.74 ALDH1A1 (0.40) ALDH1A1KMT2AHPGDMEN1SMN1; SMN2
SCHEMBL20114229 0.73
SCHEMBL6546473 0.71 NPC1 (0.51) ALDH1A1KMT2AMEN1SMN1; SMN2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018080067-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING SAME 주식회사 두산 2018-05-03 WO disclosed