SCHEMBL20114136

SCHEMBL20114136

C=C(Cc1cccc2c1oc1ccccc12)c1ccc(Br)cc1-c1ccccc1C

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 4/20 0.39
KDM4E B2RXH2 2/20 0.37
HDAC8 Q9BY41 2/20 0.34
NMUR2 Q9GZQ4 3/20 0.33
GGPS1 O95749 1/20 0.32
DRD4 P21917 1/20 0.32
ALDH1A1 P00352 2/20 0.31
THRB P10828 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
GLA P06280 1/20 0.31
STING1 Q86WV6 1/20 0.31
TP53 P04637 1/20 0.31
ABCG2 Q9UNQ0 1/20 0.31
USP2 O75604 1/20 0.30
HPGD P15428 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20114168 0.88 ALOX5 (0.41) ALOX5KDM4EHDAC8NMUR2GGPS1
SCHEMBL20114278 0.83 ALOX5 (0.41) ALOX5KDM4EHDAC8NMUR2GGPS1
SCHEMBL20114159 0.82 CYP1A2 (0.40) KDM4ENMUR2ALDH1A1MEN1KMT2A
SCHEMBL20114138 0.75 ALDH1A1 (0.36) KDM4EALDH1A1MEN1KMT2AHPGD
SCHEMBL20114602 0.74 PTGES (0.32) KDM4EALDH1A1MEN1KMT2AUSP2
SCHEMBL20114176 0.74 IDO1 (0.42) KDM4ENMUR2ALDH1A1MEN1KMT2A
SCHEMBL19346582 0.72 ALOX5 (0.44) ALOX5TP53
SCHEMBL20114097 0.71 HTR7 (0.42) ALDH1A1
SCHEMBL20114041 0.71 ALDH1A1 (0.38) ALDH1A1MEN1KMT2A
SCHEMBL20114229 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018080067-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING SAME 주식회사 두산 2018-05-03 WO disclosed