SCHEMBL20114097

SCHEMBL20114097

C=C(Cc1cccc(-c2ccccc2)c1)c1ccc(Br)cc1-c1ccccc1C

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 2/20 0.42
FFAR1 O14842 9/20 0.37
FFAR4 Q5NUL3 3/20 0.37
ALDH1A1 P00352 2/20 0.36
PLA2G10 O15496 1/20 0.33
PLA2G2A P14555 1/20 0.33
BACE1 P56817 1/20 0.33
KLKB1 P03952 1/20 0.33
KLK1 P06870 1/20 0.33
SLC6A9 P48067 1/20 0.33
SHMT1 P34896 1/20 0.33
SHMT2 P34897 1/20 0.33
ALDH2 P05091 1/20 0.33
ALDH3A1 P30838 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20114041 0.90 ALDH1A1 (0.38) HTR7FFAR1FFAR4ALDH1A1SLC6A9
SCHEMBL20114138 0.90 ALDH1A1 (0.36) HTR7ALDH1A1ALDH2ALDH3A1
SCHEMBL20114602 0.82 PTGES (0.32) FFAR1ALDH1A1BACE1
SCHEMBL20114083 0.76 NR1H4 (0.38) FFAR1ALDH1A1SLC6A9
SCHEMBL20114078 0.76 ALDH1A1 (0.40) ALDH1A1SLC6A9
SCHEMBL20114086 0.75 ADORA2A (0.37) ALDH1A1
SCHEMBL20114136 0.71 ALOX5 (0.39) ALDH1A1
SCHEMBL21425499 0.67 PLA2G10 (0.41) HTR7ALDH1A1PLA2G10PLA2G2A
SCHEMBL5932002 0.67 AGXT (0.47) SHMT1SHMT2
SCHEMBL27906006 0.67 NR4A2 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018080067-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING SAME 주식회사 두산 2018-05-03 WO disclosed