Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | USP14 | P54578 | 4/20 | 0.34 |
| ▸ | RORC | P51449 | 4/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.33 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18083369 | 0.87 | KDM4E (0.42) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL19380368 | 0.85 | USP14 (0.36) | KDM1AUSP14RORCPTGER4 | |
| SCHEMBL22920231 | 0.80 | USP14 (0.36) | KDM1AKDM4EMAPTALDH1A1HPGD | |
| SCHEMBL20116769 | 0.79 | RORC (0.36) | USP14RORCPTGER4 | |
| SCHEMBL22624275 | 0.78 | KDM4E (0.52) | KDM4EALDH1A1USP14RORCPTGER4 | |
| SCHEMBL20040430 | 0.78 | ALDH1A1 (0.45) | KDM1AKDM4EMAPTALDH1A1HSD17B10 | |
| SCHEMBL17705062 | 0.78 | PGR (0.44) | KDM1AKDM4EMAPTALDH1A1HPGD | |
| SCHEMBL20116770 | 0.78 | USP14 (0.35) | KDM4EALDH1A1USP14RORC | |
| SCHEMBL21132045 | 0.78 | KDM4E (0.39) | KDM4EALDH1A1HPGDUSP14RORC | |
| SCHEMBL18347414 | 0.77 | KDM4E (0.47) | KDM4EUSP14RORCPTGER4ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3119770-B1 | NEW DIBENZOFURANS AND DIBENZOTHIOPHENES | IDEMITSU KOSAN CO (JP) | 2018-05-02 | — | — | EP | disclosed |