Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.31 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.31 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19086308 | 0.77 | CTSL (0.43) | TRPV4MMP2ALDH1A1CYP19A1CTSL | |
| SCHEMBL25077680 | 0.74 | TRPV4 (0.38) | TRPV4MMP2ALDH1A1CYP19A1MMP3 | |
| SCHEMBL4798754 | 0.73 | ALDH1A1 (0.36) | TRPV4ALDH1A1 | |
| SCHEMBL4673669 | 0.72 | TRPV4 (0.54) | TRPV4ALDH1A1HRH4 | |
| SCHEMBL14497430 | 0.69 | ALDH1A1 (0.41) | ALDH1A1HCRTR1HCRTR2 | |
| SCHEMBL515057 | 0.67 | MMP2 (0.49) | MMP2LMNAALDH1A1MMP3 | |
| SCHEMBL11819313 | 0.67 | ALDH1A1 (0.41) | TRPV4ALDH1A1NCEH1 | |
| SCHEMBL15776319 | 0.66 | ALDH1A3 (0.45) | TRPV4LMNAALDH1A1CRHR1HRH4 | |
| SCHEMBL25077636 | 0.66 | MEN1 (0.36) | TRPV4MMP2ALDH1A1MMP3NCEH1 | |
| SCHEMBL2561546 | 0.64 | TBXAS1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081167-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS (US) | 2018-05-03 | — | — | WO | disclosed |