Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 5/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.38 |
| ▸ | CNR1 | P21554 | 3/20 | 0.37 |
| ▸ | CNR2 | P34972 | 3/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20118132 | 0.84 | LMNA (0.46) | CRHR1CRHR2HPGDPDE4B | |
| SCHEMBL18208313 | 0.83 | KMT2A (0.42) | CRHR1CRHR2ALDH1A1KMT2AHPGD | |
| SCHEMBL18208823 | 0.83 | KMT2A (0.42) | CRHR1CRHR2ALDH1A1KMT2AHPGD | |
| SCHEMBL18208311 | 0.83 | KMT2A (0.42) | CRHR1CRHR2ALDH1A1KMT2AHPGD | |
| SCHEMBL20118047 | 0.80 | RORC (0.43) | CRHR1CRHR2KMT2AHPGDPDE4B | |
| SCHEMBL20118038 | 0.79 | CRHR1 (0.41) | CRHR1CRHR2ALDH1A1KMT2AHPGD | |
| SCHEMBL20118418 | 0.79 | CRHR1 (0.40) | CRHR1CRHR2PDE4B | |
| SCHEMBL20118191 | 0.79 | CRHR1 (0.43) | CRHR1CRHR2KMT2AHPGDPDE4B | |
| SCHEMBL20118117 | 0.78 | KMT2A (0.41) | CRHR1CRHR2ALDH1A1KMT2AHPGD | |
| SCHEMBL20118187 | 0.78 | PDE4B (0.41) | CRHR1CRHR2HPGDPDE4BCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018078009-A1 | AMIDO-SUBSTITUTED CYCLOHEXANE DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-05-03 | — | — | WO | disclosed |