Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.32 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18649225 | 0.91 | KIF11 (0.40) | LMNATRPA1PTGS1CACNA1CKIF11 | |
| SCHEMBL18799899 | 0.84 | CYP1A2 (0.38) | LMNATRPA1NR1I2EGFRADRA2A | |
| SCHEMBL19546082 | 0.84 | NR1I2 (0.46) | LMNATRPA1PTGS1CACNA1CNR1I2 | |
| SCHEMBL20121768 | 0.78 | AKR1C3 (0.36) | LMNATRPA1PTGS2KIF11ALDH1A1 | |
| SCHEMBL25059000 | 0.77 | BCHE (0.38) | LMNANR1I2ALDH1A1GAAHTT | |
| SCHEMBL20647202 | 0.77 | MAT2A (0.45) | LMNAPTGS1NR1I2EGFRADRA2A | |
| SCHEMBL25882680 | 0.76 | ALKBH5 (0.42) | LMNATRPA1PTGS1CACNA1CKIF11 | |
| SCHEMBL27100914 | 0.76 | MAOA (0.35) | KIF11HTT | |
| SCHEMBL20402776 | 0.76 | GPR3 (0.41) | LMNANR1I2EGFRADRA2AADORA3 | |
| SCHEMBL12231624 | 0.75 | RORA (0.35) | LMNATRPA1PTGS1CACNA1CNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9963478-B2 | Mannose derivatives for treating bacterial infections | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2018-05-08 | — | — | US | disclosed |