Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 7/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 7/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.43 |
| ▸ | CCNC | P24863 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.41 |
| ▸ | PTGDR | Q13258 | 4/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20124820 | 0.87 | ALOX5 (0.42) | ALOX5NPC1L3MBTL1PTGER3PTGER2 | |
| SCHEMBL1150939 | 0.80 | PTGER3 (0.63) | PTGER3PTGER2PTGER4TBXA2RPTGDR | |
| SCHEMBL12075162 | 0.80 | LMNA (0.61) | PTGER3PTGER2PTGER4TBXA2RPTGDR | |
| SCHEMBL3214322 | 0.80 | PTGER3 (0.63) | PTGER3PTGER2PTGER4TBXA2RPTGDR | |
| SCHEMBL309761 | 0.80 | PTGER3 (0.63) | PTGER3PTGER2PTGER4TBXA2RPTGDR | |
| SCHEMBL19954281 | 0.79 | TRPM8 (0.48) | ALOX5CCNCCDK8NR4A2ALDH1A1 | |
| SCHEMBL3732406 | 0.79 | TRPM8 (0.48) | ALOX5CCNCCDK8NR4A2ALDH1A1 | |
| SCHEMBL27680267 | 0.79 | PTGER3 (0.45) | PTGER3PTGER2PTGER4TBXA2RPTGDR | |
| SCHEMBL27667797 | 0.79 | PTGER3 (0.45) | PTGER3PTGER2PTGER4TBXA2RPTGDR | |
| SCHEMBL780429 | 0.78 | IAPP (0.47) | ALOX5PTGER3PTGER2PTGER4TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3008045-B1 | ANTIBACTERIAL THIAZOLECARBOXYLIC ACIDS | ANTABIO SAS (FR) | 2018-05-09 | — | — | EP | disclosed |