Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CCNC | P24863 | 1/20 | 0.44 |
| ▸ | CDK8 | P49336 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19954281 | 1.00 | TRPM8 (0.48) | TRPM8ALOX5ALDH1A1TSHRRAB9A | |
| SCHEMBL17833498 | 0.87 | TRPM8 (0.47) | TRPM8ALOX5ALDH1A1TSHRRAB9A | |
| SCHEMBL28379416 | 0.81 | NPC1 (0.63) | TRPM8ALDH1A1TSHRRAB9ALMNA | |
| SCHEMBL5598954 | 0.80 | NFE2L2 (0.61) | ALDH1A1TSHRRAB9ALMNAKDM4E | |
| SCHEMBL5598952 | 0.80 | NFE2L2 (0.61) | ALDH1A1TSHRRAB9ALMNAKDM4E | |
| SCHEMBL4105481 | 0.80 | HDAC1 (0.57) | ALDH1A1RAB9ALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL28375645 | 0.80 | HSD11B1 (0.65) | ALOX5ALDH1A1LMNAKDM4ECCNC | |
| SCHEMBL20124823 | 0.79 | ALOX5 (0.44) | ALOX5ALDH1A1LMNACCNCCDK8 | |
| SCHEMBL2834883 | 0.79 | MAPT (0.66) | TRPM8ALDH1A1TSHRRAB9ALMNA | |
| SCHEMBL78556 | 0.79 | CA1 (0.62) | ALDH1A1TSHRRAB9ALMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111018735-B | Preparation method of cinnamamide compound | 河南农业大学 | 2021-09-07 | — | — | CN | disclosed |
| CN-111018735-A | Preparation method of cinnamamide | 河南农业大学 | 2020-04-17 | — | — | CN | disclosed |
| US-20100278876-A1 | HIGH-SOLID ANTIFOULING PAINT COMPOSITION, ANTIFOULING COATING FILM, BASE MATERIAL WITH COATING FILM, ANTIFOULING BASE MATERIAL, METHOD FOR FORMING COATING FILM ON SURFACE OF BASE MATERIAL, ANTIFOULING METHOD FOR BASE MATERIAL, AND HIGH-SOLID MULTI-PACKAGE ANTIFOULING PAINT COMPOSITION SET | CHUGOKU MARINE PAINTS, LTD. (JP) | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100278876-A1 | HIGH-SOLID ANTIFOULING PAINT COMPOSITION, ANTIFOULING COATING FILM, BASE MATERIAL WITH COATING FILM, ANTIFOULING BASE MATERIAL, METHOD FOR FORMING COATING FILM ON SURFACE OF BASE MATERIAL, ANTIFOULING METHOD FOR BASE MATERIAL, AND HIGH-SOLID MULTI-PACKAGE ANTIFOULING PAINT COMPOSITION SET | PABPC1, MBOAT1, PCMT1 | TRPM8 555/4885ALOX5 2067/4885ALDH1A1 1187/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.