Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CCNC | P24863 | 1/20 | 0.44 |
| ▸ | CDK8 | P49336 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3732406 | 1.00 | TRPM8 (0.48) | TRPM8ALOX5ALDH1A1TSHRRAB9A | |
| SCHEMBL17833498 | 0.87 | TRPM8 (0.47) | TRPM8ALOX5ALDH1A1TSHRRAB9A | |
| SCHEMBL28379416 | 0.81 | NPC1 (0.63) | TRPM8ALDH1A1TSHRRAB9ALMNA | |
| SCHEMBL5598954 | 0.80 | NFE2L2 (0.61) | ALDH1A1TSHRRAB9ALMNAKDM4E | |
| SCHEMBL5598952 | 0.80 | NFE2L2 (0.61) | ALDH1A1TSHRRAB9ALMNAKDM4E | |
| SCHEMBL4105481 | 0.80 | HDAC1 (0.57) | ALDH1A1RAB9ALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL28375645 | 0.80 | HSD11B1 (0.65) | ALOX5ALDH1A1LMNAKDM4ECCNC | |
| SCHEMBL20124823 | 0.79 | ALOX5 (0.44) | ALOX5ALDH1A1LMNACCNCCDK8 | |
| SCHEMBL2834883 | 0.79 | MAPT (0.66) | TRPM8ALDH1A1TSHRRAB9ALMNA | |
| SCHEMBL78556 | 0.79 | CA1 (0.62) | ALDH1A1TSHRRAB9ALMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9914712-B2 | Antibacterial thiazolecarboxylic acids | ANTABIO SAS (FR) | 2018-03-13 | — | — | US | disclosed |