Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 3/20 | 0.48 |
| ▸ | NOS2 | P35228 | 3/20 | 0.48 |
| ▸ | NOS1 | P29475 | 2/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | CCR8 | P51685 | 1/20 | 0.31 |
| ▸ | IKBKB | O14920 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12647715 | 0.80 | NOS3 (0.56) | NOS3NOS2NOS1CYP2A6LMNA | |
| SCHEMBL31587245 | 0.80 | NOS3 (0.56) | NOS3NOS2NOS1CYP2A6LMNA | |
| SCHEMBL20801738 | 0.77 | DHFR (0.30) | — | |
| SCHEMBL19737664 | 0.77 | DGAT1 (0.31) | — | |
| SCHEMBL13283349 | 0.76 | NOS3 (0.56) | NOS3NOS2NOS1CYP2A6LMNA | |
| SCHEMBL17480023 | 0.75 | NOS3 (0.54) | NOS3NOS2NOS1CYP2A6LMNA | |
| SCHEMBL20465810 | 0.75 | NOS3 (0.54) | NOS3NOS2NOS1CYP2A6LMNA | |
| SCHEMBL20465809 | 0.73 | LMNA (0.55) | NOS3NOS2NOS1CYP2A6LMNA | |
| SCHEMBL20125018 | 0.72 | NOS3 (0.50) | NOS3NOS2NOS1CYP2A6LMNA | |
| SCHEMBL20124986 | 0.72 | NOS3 (0.50) | NOS3NOS2NOS1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3318557-A2 | QUINOLONE COMPOUND | Otsuka Pharmaceutical Co., Ltd. (JP) | 2018-05-09 | — | — | EP | disclosed |