Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL84356 | 0.82 | NOS3 (0.40) | DHFR | |
| SCHEMBL18657377 | 0.79 | DHFR (0.33) | DHFR | |
| SCHEMBL20125035 | 0.77 | NOS3 (0.48) | — | |
| SCHEMBL14864222 | 0.77 | TBK1 (0.40) | DHFR | |
| SCHEMBL22945605 | 0.75 | SLC6A2 (0.36) | DHFR | |
| SCHEMBL20801904 | 0.75 | CYP1A2 (0.43) | DHFR | |
| SCHEMBL19737664 | 0.73 | DGAT1 (0.31) | DHFR | |
| SCHEMBL15471948 | 0.70 | HTT (0.42) | DHFR | |
| SCHEMBL29910000 | 0.69 | GABRA1 (0.38) | DHFR | |
| SCHEMBL84407 | 0.69 | NOS3 (0.56) | DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190077762-A1 | QUINOLONE COMPOUND | OTSUKA PHARMA CO LTD (JP) | 2019-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190077762-A1 | QUINOLONE COMPOUND | HAX1, NQO2, NHERF1 | DHFR 1053/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.