SCHEMBL2012649

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2009298	0.83	ALDH1A1 (0.41)	ALDH1A1HPGDCYP3A4TDP1COXFA4
	SCHEMBL12580741	0.77	ALDH1A1 (0.43)	ALDH1A1HPGDCYP3A4TDP1COXFA4
	SCHEMBL2011114	0.76	ALDH1A1 (0.42)	ALDH1A1HPGDCYP3A4TDP1HIF1A
	Fumaric Acid SCHEMBL17095081	0.75	ALDH1A1 (0.42)	ALDH1A1HPGDCYP3A4TDP1HIF1A
	SCHEMBL2888860	0.74	—	—
	SCHEMBL142467	0.74	—	—
	SCHEMBL2007092	0.74	KDM4E (0.40)	ALDH1A1HPGDCYP3A4TDP1HIF1A
	SCHEMBL17829468	0.74	ALDH1A1 (0.40)	ALDH1A1HPGDCYP3A4TDP1HIF1A
	Malic Acid SCHEMBL17781489	0.72	ALDH1A1 (0.37)	ALDH1A1HPGDCYP3A4TDP1HIF1A
	SCHEMBL27665986	0.71	COXFA4 (0.57)	ALDH1A1HPGDCYP3A4TDP1COXFA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.