Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 10/20 | 0.38 |
| ▸ | LMNA | P02545 | 8/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.37 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GFPT1 | Q06210 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20128467 | 0.87 | HCAR2 (0.54) | HCAR2KEAP1NFE2L2MAPTLMNA | |
| SCHEMBL20128472 | 0.80 | MAPT (0.42) | HCAR2KEAP1NFE2L2MAPTLMNA | |
| SCHEMBL20128470 | 0.76 | LMNA (0.49) | HCAR2KEAP1NFE2L2MAPTLMNA | |
| SCHEMBL20128471 | 0.71 | MAPT (0.43) | HCAR2KEAP1NFE2L2MAPTLMNA | |
| SCHEMBL20128468 | 0.71 | ALDH1A1 (0.46) | HCAR2KEAP1NFE2L2MAPTLMNA | |
| SCHEMBL20129402 | 0.69 | MAPT (0.40) | MAPTLMNAKDM4EHTTMDM2 | |
| SCHEMBL20129401 | 0.69 | LMNA (0.40) | MAPTLMNAKDM4EHTTMDM2 | |
| SCHEMBL20129342 | 0.68 | MAPT (0.50) | HCAR2KEAP1NFE2L2MAPTLMNA | |
| SCHEMBL20129338 | 0.68 | ALDH1A1 (0.52) | HCAR2KEAP1NFE2L2MAPTLMNA | |
| SCHEMBL10898624 | 0.67 | HCAR2 (0.65) | HCAR2KEAP1NFE2L2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180126784-A1 | RUBBER COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180126784-A1 | RUBBER COMPOSITION | RER1, KPNB1, KPNA1 | HCAR2 3674/4885KEAP1 621/4885NFE2L2 3854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.