Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.54 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 6/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 9/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.44 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20128473 | 0.87 | HCAR2 (0.41) | HCAR2KEAP1NFE2L2LMNAHTT | |
| SCHEMBL20128471 | 0.82 | MAPT (0.43) | HCAR2KEAP1NFE2L2LMNAHTT | |
| SCHEMBL20129342 | 0.79 | MAPT (0.50) | HCAR2KEAP1NFE2L2LMNAHTT | |
| SCHEMBL20129338 | 0.78 | ALDH1A1 (0.52) | HCAR2KEAP1NFE2L2LMNAHTT | |
| SCHEMBL20129016 | 0.75 | ALDH1A1 (0.66) | HCAR2KEAP1NFE2L2LMNAHTT | |
| SCHEMBL20129844 | 0.75 | ALDH1A1 (0.66) | HCAR2KEAP1NFE2L2LMNAHTT | |
| SCHEMBL20129482 | 0.75 | ALDH1A1 (0.66) | HCAR2KEAP1NFE2L2LMNAHTT | |
| SCHEMBL20129341 | 0.75 | MAPT (0.49) | HCAR2KEAP1NFE2L2LMNAHTT | |
| SCHEMBL21964229 | 0.74 | LMNA (0.53) | HCAR2KEAP1NFE2L2LMNAHTT | |
| Dimethyl Fumarate SCHEMBL41836 | 0.74 | NFE2L2 (1.00) | HCAR2KEAP1NFE2L2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180126784-A1 | RUBBER COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180126784-A1 | RUBBER COMPOSITION | RER1, KPNB1, KPNA1 | HCAR2 3674/4885KEAP1 621/4885NFE2L2 3854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.