Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.36 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | TGM2 | P21980 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10537910 | 0.98 | TSHR (0.42) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| Hydrochloric Acid SCHEMBL30729583 | 0.88 | TSHR (0.42) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| Hydrochloric Acid SCHEMBL28025704 | 0.83 | TSHR (0.38) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL16356914 | 0.83 | ZDHHC20 (0.43) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| Hydrochloric Acid SCHEMBL8575188 | 0.81 | TSHR (0.39) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL16356899 | 0.80 | ZDHHC20 (0.49) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| Hydrochloric Acid SCHEMBL336794 | 0.79 | ZDHHC20 (0.46) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| Hydrochloric Acid SCHEMBL4534755 | 0.78 | TSHR (0.46) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| Hydrochloric Acid SCHEMBL27944735 | 0.77 | TSHR (0.42) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| Hydrochloric Acid SCHEMBL15843887 | 0.77 | TSHR (0.45) | TSHRALDH1A1MAPK1TDP1ZDHHC20 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805824-A | Multifunctional concrete additive and preparation method and application thereof | 苏光伟 | 2022-07-29 | — | — | CN | claimed |
| US-12515213-B2 | Membranes and their uses | FUJIFILM MANUFACTURING EUROPE B.V. (NL) | 2026-01-06 | — | — | US | disclosed |
| US-12157972-B2 | Textile printing ink | Konica Minolta, Inc. (JP) | 2024-12-03 | — | — | US | disclosed |
| CN-115244089-B | Film and use thereof | 富士胶片制造欧洲有限公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-115210270-B | Film and use thereof | 富士胶片制造欧洲有限公司 | 2024-06-04 | — | — | CN | disclosed |
| CN-116133865-A | Aqueous inkjet ink and method for printing fiber structure by inkjet method | 山阳色素株式会社 | 2023-05-16 | — | — | CN | disclosed |
| US-20230138382-A1 | Membranes and Their Uses | FUJIFILM MANUFACTURING EUROPE B.V. (NL) | 2023-05-04 | — | — | US | disclosed |
| US-20230107868-A1 | Membranes and Their Uses | FUJIFILM MANUFACTURING EUROPE B.V. (NL) | 2023-04-06 | — | — | US | disclosed |
| CN-114805824-B | Multifunctional concrete additive and preparation method and application thereof | 苏光伟 | 2023-02-07 | — | — | CN | disclosed |
| CN-114805824-B | Multifunctional concrete additive and preparation method and application thereof | 苏光伟 | 2023-02-07 | — | — | CN | disclosed |
| EP-2350150-B1 | CURABLE COMPOSITIONS AND MEMBRANES | FUJIFILM MFG EUROPE BV (NL) | 2012-08-22 | — | — | EP | disclosed |
| WO-2012085541-A2 | INKS & PRINTING PROCESS | FUJIFILM IMAGING COLORANTS LIMITED (GB) | 2012-06-28 | — | — | WO | disclosed |
| EP-2361271-A1 | CURABLE COMPOSITIONS AND MEMBRANES | Fujifilm Manufacturing Europe BV (NL) | 2011-08-31 | — | — | EP | disclosed |
| EP-2361270-A1 | CURABLE COMPOSITIONS AND MEMBRANES | Fujifilm Manufacturing Europe BV (NL) | 2011-08-31 | — | — | EP | disclosed |
| EP-2350150-A1 | CURABLE COMPOSITIONS AND MEMBRANES | Fujifilm Manufacturing Europe BV (NL) | 2011-08-03 | — | — | EP | disclosed |
| WO-2011073641-A1 | CURABLE COMPOSITIONS AND MEMBRANES | FUJIFILM MANUFACTURING EUROPE BV (NL) | 2011-06-23 | — | — | WO | disclosed |
| WO-2011073640-A1 | CURABLE COMPOSITIONS AND MEMBRANES | FUJIFILM MANUFACTURING EUROPE BV (NL) | 2011-06-23 | — | — | WO | disclosed |
| WO-2011073638-A1 | CURABLE COMPOSITIONS AND MEMBRANES | FUJIFILM MANUFACTURING EUROPE BV (NL) | 2011-06-23 | — | — | WO | disclosed |
| US-4888396-A | SWELLING, HEATING | POLYPURE, INC. (US) | 1989-12-19 | — | — | US | disclosed |
| US-4777218-A | WASTE WATER TREATMENT | ALLIED-SIGNAL INC. (US) | 1988-10-11 | — | — | US | disclosed |