Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.44 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9451758 | 0.98 | TSHR (0.48) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| Hydrochloric Acid SCHEMBL336794 | 0.85 | ZDHHC20 (0.46) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL4126549 | 0.82 | ZDHHC20 (0.47) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| Hydrochloric Acid SCHEMBL2869922 | 0.82 | TSHR (0.48) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| Hydrochloric Acid SCHEMBL1473578 | 0.81 | ALDH1A1 (0.52) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| Bromide SCHEMBL25324391 | 0.81 | ZDHHC20 (0.46) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| Hydrochloric Acid SCHEMBL17414844 | 0.81 | ZDHHC20 (0.50) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| Hydrochloric Acid SCHEMBL30729583 | 0.79 | TSHR (0.42) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL29142619 | 0.79 | ZDHHC20 (0.53) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| Hydrochloric Acid SCHEMBL27944735 | 0.79 | TSHR (0.42) | TSHRALDH1A1MAPK1TDP1ZDHHC20 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260117114-A1 | Method of Improving Performance of Relative Permeability Modifiers | BAKER HUGHES OILFIELD OPERATIONS LLC (US) | 2026-04-30 | — | — | US | disclosed |
| EP-3673990-A1 | CHROMATOGRAPHY PACKING FOR SEPARATION AND/OR DETECTION OF METHYLATED DNA | Sekisui Medical Co., Ltd. (JP) | 2020-07-01 | — | — | EP | disclosed |
| US-20200172971-A1 | CHROMATOGRAPHY PACKING FOR SEPARATION AND/OR DETECTION OF METHYLATED DNA | SEKISUI MEDICAL CO., LTD. (JP) | 2020-06-04 | — | — | US | disclosed |
| US-9458370-B2 | Methods for pre-emptively controlling undesirable water production from an oil or gas well | BAKER HUGHES INCORPORATED (US) | 2016-10-04 | — | — | US | disclosed |
| US-20090093382-A1 | Methods and Compositions for Pre-emptively Controlling Undesirable Water Production From Oil and Gas Wells` | BAKER HUGHES HOLDINGS LLC | 2009-04-09 | — | — | US | disclosed |
| US-20040177957-A1 | Organosilicon containing compositions for enhancing hydrocarbon production and method of using the same | BAKER HUGHES, A GE COMPANY, LLC | 2004-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260117114-A1 | Method of Improving Performance of Relative Permeability Modifiers | MYH10, MYH14, NIM1K | TSHR 2195/4885ALDH1A1 4375/4885MAPK1 1282/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.