Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.37 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TGM2 | P21980 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL336794 | 0.84 | ZDHHC20 (0.46) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL4126549 | 0.81 | ZDHHC20 (0.47) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| Acrylamide SCHEMBL28870529 | 0.81 | ZDHHC20 (0.41) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| Bromide SCHEMBL25324391 | 0.80 | ZDHHC20 (0.46) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| Hydrochloric Acid SCHEMBL4534755 | 0.79 | TSHR (0.46) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| Hydrochloric Acid SCHEMBL8575188 | 0.79 | TSHR (0.39) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL29142619 | 0.79 | ZDHHC20 (0.53) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| Chloromethane SCHEMBL28028247 | 0.79 | ZDHHC20 (0.44) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| Hydrochloric Acid SCHEMBL28470855 | 0.78 | ZDHHC20 (0.57) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| Acrylic Acid SCHEMBL396773 | 0.78 | ZDHHC20 (0.41) | TSHRALDH1A1MAPK1TDP1ZDHHC20 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115244089-A | Membrane and use thereof | 富士胶片制造欧洲有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-115210270-A | Membrane and use thereof | 富士胶片制造欧洲有限公司 | 2022-10-18 | — | — | CN | disclosed |
| CN-107849275-B | Ion exchange membrane | 富士胶片制造欧洲有限公司 | 2021-11-02 | — | — | CN | disclosed |
| CN-107849274-B | Ion exchange membrane | 富士胶片制造欧洲有限公司 | 2020-12-29 | — | — | CN | disclosed |
| CN-103717296-A | Composite membrane | FUJIFILM MFG EUROPE BV | 2014-04-09 | — | — | CN | disclosed |