Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.35 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30729583 | 0.83 | TSHR (0.42) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| Hydrochloric Acid SCHEMBL2012873 | 0.81 | TSHR (0.41) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| Hydrochloric Acid SCHEMBL336794 | 0.81 | ZDHHC20 (0.46) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| Hydrochloric Acid SCHEMBL27944735 | 0.79 | TSHR (0.42) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL10537910 | 0.79 | TSHR (0.42) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL4126549 | 0.79 | ZDHHC20 (0.47) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| Bromide SCHEMBL25324391 | 0.77 | ZDHHC20 (0.46) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| Hydrochloric Acid SCHEMBL4534755 | 0.77 | TSHR (0.46) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL29142619 | 0.76 | ZDHHC20 (0.53) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| Chloromethane SCHEMBL28028247 | 0.76 | ZDHHC20 (0.44) | TSHRALDH1A1MAPK1TDP1ZDHHC20 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250319440-A1 | ELECTRODIALYSIS CELL AND METHOD FOR LITHIUM SEPARATION | UNIV MASSACHUSETTS (US) | 2025-10-16 | — | — | US | disclosed |
| WO-1997049766-A9 | MECHANICALLY STABLE SELF-INVERTING WATER-IN-OIL POLYMER EMULSIONS | — | 1998-10-15 | — | — | WO | disclosed |
| US-5679740-A | Mechanically stable self inverting water-in-oil polymer emulsions containing carboxylated ethoxylated phenols or alcohols | CYTEC TECHNOLOGY CORP. (US) | 1997-10-21 | — | — | US | disclosed |
| EP-0308109-A1 | Electrically conductive polymer compositions, processes and polymers useful for preparing the polymer compositions | THE DOW CHEMICAL COMPANY (US) | 1989-03-22 | — | — | EP | disclosed |