SCHEMBL201298

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27738192	0.81	PARP15 (0.54)	PARP15PARP10RAB9ALMNANPC1
	SCHEMBL202084	0.79	SLC1A3 (0.41)	LMNATDP1HTT
	SCHEMBL202848	0.76	TNKS2 (0.37)	RAB9ALMNAHTT
	SCHEMBL201858	0.75	BTK (0.38)	RAB9ANPC1BACE1ACACBGRM5
	SCHEMBL203215	0.75	ROCK2 (0.37)	RAB9ALMNANPC1HTTKDM4E
	SCHEMBL12432971	0.74	TNKS2 (0.34)	PARP15PARP10LMNATDP1HTT
	SCHEMBL19285699	0.74	KDM1A (0.50)	PARP10LMNANPC1HTT
	SCHEMBL2316056	0.73	ALDH1A1 (0.52)	RAB9ALMNANPC1SMN1; SMN2HTT
	SCHEMBL2316902	0.73	AGXT (0.50)	RAB9ALMNANPC1HTT
	SCHEMBL31609727	0.73	MAPK1 (0.46)	PARP10RAB9ALMNANPC1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.