Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 13/20 | 0.41 |
| ▸ | RXRA | P19793 | 2/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19988357 | 0.90 | CYP19A1 (0.41) | CYP19A1RXRAGRIN1GRIN2BNPC1 | |
| SCHEMBL23191362 | 0.83 | CYP19A1 (0.37) | CYP19A1 | |
| SCHEMBL13453649 | 0.82 | CYP19A1 (0.45) | CYP19A1NPC1 | |
| SCHEMBL19988358 | 0.82 | CYP19A1 (0.36) | CYP19A1 | |
| SCHEMBL13949853 | 0.80 | CYP19A1 (0.44) | CYP19A1RXRAGRIN1GRIN2B | |
| SCHEMBL21790466 | 0.79 | CYP19A1 (0.43) | CYP19A1 | |
| SCHEMBL16941584 | 0.79 | CYP19A1 (0.43) | CYP19A1 | |
| SCHEMBL15096767 | 0.77 | P2RX7 (0.49) | CYP19A1 | |
| SCHEMBL21166169 | 0.77 | HDAC1 (0.35) | RXRAGRIN1GRIN2BNPC1 | |
| SCHEMBL19841389 | 0.77 | CYP19A1 (0.36) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230285310-A1 | COMPOSITIONS FOR THE DELIVERY OF PAYLOAD MOLECULES TO AIRWAY EPITHELIUM | ARES CAPITAL CORPORATION, AS AGENT | 2023-09-14 | — | — | US | disclosed |
| US-20230285310-A1 | COMPOSITIONS FOR THE DELIVERY OF PAYLOAD MOLECULES TO AIRWAY EPITHELIUM | ARES CAPITAL CORPORATION, AS AGENT | 2023-09-14 | — | — | US | disclosed |
| US-20230203087-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-06-29 | — | — | US | disclosed |
| US-10286091-B2 | Dendri-TAC and their use as theranostics | UNIVERSITE D'AVIGNON ET DES PAYS DU VAUCLUSE (FR) | 2019-05-14 | — | — | US | disclosed |
| US-20180126011-A1 | DENDRI-TAC AND THEIR USE AS THERANOSTICS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-05-10 | — | — | US | disclosed |
| US-20180126011-A1 | DENDRI-TAC AND THEIR USE AS THERANOSTICS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180126011-A1 | DENDRI-TAC AND THEIR USE AS THERANOSTICS | DBI, CDIPT, DGKI | CYP19A1 2927/4885RXRA 1783/4885GRIN1 3691/4885 |
| US-20230203087-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | RNGTT, NSUN2, ALKBH1 | CYP19A1 3601/4885RXRA 1709/4885GRIN1 3997/4885 |
| US-20230285310-A1 | COMPOSITIONS FOR THE DELIVERY OF PAYLOAD MOLECULES TO AIRWAY EPITHELIUM | CFTR, TSLP, MTREX | CYP19A1 4799/4885RXRA 2120/4885GRIN1 4788/4885 |
| US-10286091-B2 | Dendri-TAC and their use as theranostics | DBI, CDIPT, DGKI | CYP19A1 2927/4885RXRA 1783/4885GRIN1 3691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.