Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2015518 | 0.83 | ADORA1 (0.32) | — | |
| SCHEMBL2013162 | 0.80 | FBP1 (0.36) | FBP1 | |
| SCHEMBL2014650 | 0.79 | — | — | |
| SCHEMBL2017946 | 0.75 | LMNA (0.37) | FBP1 | |
| SCHEMBL2014020 | 0.70 | MEN1 (0.35) | FBP1 | |
| SCHEMBL22121304 | 0.66 | MGMT (0.38) | — | |
| Ammonia Solution, Strong SCHEMBL4939360 | 0.65 | MGMT (0.37) | — | |
| SCHEMBL2015218 | 0.64 | CDC7 (0.40) | — | |
| SCHEMBL3907818 | 0.64 | AR (0.41) | — | |
| SCHEMBL2015516 | 0.64 | TRPM8 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011075630-A1 | SUBSTITUTED FUSED ARYL AND HETEROARYL DERIVATIVES AS PI3K INHIBITORS | INCYTE CORPORATION (US) | 2011-06-23 | — | — | WO | disclosed |