Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 8/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.42 |
| ▸ | TNF | P01375 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29688609 | 1.00 | AKR1B1 (0.44) | AKR1B1PTGER3TNFLMNAAKR1A1 | |
| SCHEMBL10263653 | 0.83 | PTGER3 (0.41) | AKR1B1PTGER3TNFLMNAAKR1A1 | |
| SCHEMBL1970646 | 0.80 | LMNA (0.59) | AKR1B1PTGER3TNFLMNAAKR1A1 | |
| SCHEMBL20135334 | 0.79 | LMNA (0.42) | PTGER3TNFLMNA | |
| SCHEMBL29688911 | 0.79 | LMNA (0.42) | PTGER3TNFLMNA | |
| SCHEMBL15974325 | 0.78 | LMNA (0.47) | AKR1B1PTGER3TNFLMNA | |
| SCHEMBL15535570 | 0.78 | AKR1B1 (0.49) | AKR1B1PTGER3AKR1A1 | |
| SCHEMBL15535569 | 0.78 | AKR1B1 (0.49) | AKR1B1PTGER3AKR1A1 | |
| SCHEMBL1093500 | 0.77 | LMNA (0.43) | AKR1B1PTGER3TNFLMNAAKR1A1 | |
| SCHEMBL192001 | 0.76 | AKR1B1 (0.44) | AKR1B1PTGER3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922347-B | Novel imide derivatives and their use as pharmaceuticals | 田边三菱制药株式会社 | 2022-06-28 | — | — | CN | disclosed |
| US-10407408-B2 | Imide derivatives and use thereof as medicine | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2019-09-10 | — | — | US | disclosed |
| US-20190077787-A1 | NOVEL IMIDE DERIVATIVES AND USE THEREOF AS MEDICINE | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2019-03-14 | — | — | US | disclosed |
| EP-3321256-A1 | NOVEL IMIDE DERIVATIVES AND USE THEREOF AS MEDICINE | Mitsubishi Tanabe Pharma Corporation (JP) | 2018-05-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190077787-A1 | NOVEL IMIDE DERIVATIVES AND USE THEREOF AS MEDICINE | MMP9, MMP10, MMP1 | AKR1B1 2158/4885PTGER3 224/4885TNF 33/4885 |
| US-10407408-B2 | Imide derivatives and use thereof as medicine | MMP9, MMP2, MMP1 | AKR1B1 2142/4885PTGER3 190/4885TNF 29/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.