Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28876785 | 0.98 | MAPT (0.46) | TP53CYP1A2CYP3A4CYP2D6PKM | |
| SCHEMBL17913377 | 0.88 | S1PR5 (0.44) | CYP1A2CYP2D6NFKB1LMNAALDH1A1 | |
| SCHEMBL19514340 | 0.87 | LTA4H (0.47) | HRH3LTA4HLMNAPMP22SMN1; SMN2 | |
| SCHEMBL3794817 | 0.81 | SLC18A3 (0.47) | HRH3LTA4HLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL25262763 | 0.79 | LTA4H (0.43) | HRH3LTA4HLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL1077689 | 0.79 | GNAI3 (0.49) | HRH3LTA4HLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL458560 | 0.79 | SMN1; SMN2 (0.61) | LTA4HLMNASMN1; SMN2L3MBTL1S1PR5 | |
| SCHEMBL28783148 | 0.79 | LTA4H (0.43) | HRH3LTA4HLMNAPMP22SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5065549 | 0.78 | SMN1; SMN2 (0.64) | LTA4HLMNASMN1; SMN2L3MBTL1S1PR5 | |
| SCHEMBL2061566 | 0.78 | LMNA (0.45) | HRH3LTA4HLMNASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118159526-A | Process for preparing chloroalkyl substituted cyclic amines | 好利安药理股份公司 | 2024-06-07 | — | — | CN | claimed |
| CN-110167931-A | Method for preparing umeclidinium bromide | 好利安科技有限公司 | 2019-08-23 | — | — | CN | claimed |
| US-20240383854-A1 | PROCESS FOR THE PREPARATION OF CHLOROALKYL SUBSTITUTED CYCLIC AMINES | HOVIONE FARMACIENCIA SA (PT) | 2024-11-21 | — | — | US | disclosed |
| EP-4392411-A1 | PROCESS FOR THE PREPARATION OF CHLOROALKYL SUBSTITUTED CYCLIC AMINES | Hovione Farmaciencia SA (PT) | 2024-07-03 | — | — | EP | disclosed |
| WO-2023030667-A1 | PROCESS FOR THE PREPARATION OF CHLOROALKYL SUBSTITUTED CYCLIC AMINES | HOVIONE SCIENTIA (IE) | 2023-03-09 | — | — | WO | disclosed |
| CN-115385906-A | Method for preparing umeclidinium bromide | 好利安科技有限公司 | 2022-11-25 | — | — | CN | disclosed |
| CN-112479983-B | Wumei ammonium bromide intermediate and preparation method thereof | 江苏豪森药业集团有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-111484445-B | Method for separating and purifying intermediate of high-purity Wumei ammonium bromide | 广东莱佛士制药技术有限公司 | 2021-05-18 | — | — | CN | disclosed |
| CN-111484445-B | Method for separating and purifying intermediate of high-purity Wumei ammonium bromide | 广东莱佛士制药技术有限公司 | 2021-05-18 | — | — | CN | disclosed |
| CN-112479983-A | Wumei ammonium bromide intermediate and preparation method thereof | 江苏豪森药业集团有限公司 | 2021-03-12 | — | — | CN | disclosed |
| CN-111484445-A | Method for synthesizing intermediate of high-purity Wumei ammonium bromide | 广东莱佛士制药技术有限公司 | 2020-08-04 | — | — | CN | disclosed |
| CN-111484445-A | Method for synthesizing intermediate of high-purity Wumei ammonium bromide | 广东莱佛士制药技术有限公司 | 2020-08-04 | — | — | CN | disclosed |
| EP-3538524-A1 | PROCESS FOR THE PREPARATION OF UMECLIDINIUM BROMIDE | Hovione Scientia Limited (IE) | 2019-09-18 | — | — | EP | disclosed |
| CN-110167931-A | Method for preparing umeclidinium bromide | 好利安科技有限公司 | 2019-08-23 | — | — | CN | disclosed |
| CN-110167931-A | Method for preparing umeclidinium bromide | 好利安科技有限公司 | 2019-08-23 | — | — | CN | disclosed |
| WO-2018087561-A1 | PROCESS FOR THE PREPARATION OF UMECLIDINIUM BROMIDE | HOVIONE SCIENTIA LIMITED (IE) | 2018-05-17 | — | — | WO | disclosed |
| CN-107935917-A | A kind of synthetic method of 1 (2 chloroethyl) 4 piperidinecarboxylic acid ester | 广东莱佛士制药技术有限公司 | 2018-04-20 | — | — | CN | disclosed |
| CN-102040602-A | Muscarinic acetylcholine receptor antagonists | GLAXO GROUP LTD | 2011-05-04 | — | — | CN | disclosed |
| CN-1976701-A | Muscarinic acetylcholine receptor antagonists | GLAXO GROUP LTD (GB) | 2007-06-06 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240383854-A1 | PROCESS FOR THE PREPARATION OF CHLOROALKYL SUBSTITUTED CYCLIC AMINES | ETFB, TOP2B, MGMT | TP53 1390/4885CYP1A2 26/4885CYP3A4 134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.