Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRPF1 | P55201 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | BIRC2 | Q13490 | 3/20 | 0.34 |
| ▸ | XIAP | P98170 | 2/20 | 0.34 |
| ▸ | MLNR | O43193 | 3/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20142226 | 0.89 | BRPF1 (0.35) | BRPF1BRD4BIRC2MEN1GAA | |
| SCHEMBL20142224 | 0.88 | BRPF1 (0.33) | BRPF1BRD4BIRC2XIAPSLC6A9 | |
| SCHEMBL20141640 | 0.76 | HTR1A (0.40) | MLNRDRD2LMNAADRB1HTR1A | |
| SCHEMBL20157162 | 0.75 | BRPF1 (0.39) | BRPF1BRD4MEN1GAAKMT2A | |
| SCHEMBL20141638 | 0.74 | HTR1A (0.41) | MLNRDRD2LMNAADRB1HTR1A | |
| SCHEMBL5745275 | 0.70 | BRPF1 (0.53) | BRPF1BRD4BIRC2XIAPMEN1 | |
| SCHEMBL2459077 | 0.69 | NCF1 (0.49) | BRPF1BRD4BIRC2DRD2ALDH1A1 | |
| SCHEMBL2459075 | 0.69 | NCF1 (0.49) | BRPF1BRD4BIRC2DRD2ALDH1A1 | |
| SCHEMBL5745220 | 0.68 | BRPF1 (0.47) | BRPF1BRD4BIRC2GAAALDH1A1 | |
| SCHEMBL11106905 | 0.66 | ALDH1A1 (0.46) | BRPF1BRD4BIRC2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |