Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRPF1 | P55201 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 4/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | KHK | P50053 | 2/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140670 | 0.75 | BRPF1 (0.37) | BRPF1BRD4MEN1GAAKMT2A | |
| SCHEMBL2459077 | 0.73 | NCF1 (0.49) | BRPF1BRD4ADRA2AADRA2BADRA2C | |
| SCHEMBL2459075 | 0.73 | NCF1 (0.49) | BRPF1BRD4ADRA2AADRA2BADRA2C | |
| SCHEMBL20142226 | 0.72 | BRPF1 (0.35) | BRPF1BRD4MEN1GAAKMT2A | |
| SCHEMBL5105811 | 0.71 | ALDH1A1 (0.39) | ALDH1A1LMNAHTR1A | |
| SCHEMBL25407029 | 0.69 | DRD2 (0.64) | BRPF1BRD4MAPTALDH1A1LMNA | |
| SCHEMBL27680822 | 0.69 | DRD2 (0.64) | BRPF1BRD4MAPTALDH1A1LMNA | |
| SCHEMBL5105809 | 0.68 | XIAP (0.41) | BRPF1BRD4GAAMAPTALDH1A1 | |
| SCHEMBL8370464 | 0.67 | HTR1A (0.54) | MAPTLMNAHTR1ASLC6A4SLC6A2 | |
| SCHEMBL21281577 | 0.67 | ADRB1 (0.61) | MAPTALDH1A1LMNAHTR1AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |