Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRPF1 | P55201 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.32 |
| ▸ | XIAP | P98170 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | RBP4 | P02753 | 1/20 | 0.30 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140670 | 0.88 | BRPF1 (0.37) | BRPF1BRD4BIRC2XIAPMEN1 | |
| SCHEMBL20141638 | 0.88 | HTR1A (0.41) | LMNA | |
| SCHEMBL20142226 | 0.81 | BRPF1 (0.35) | BRPF1BRD4BIRC2MEN1GAA | |
| SCHEMBL20141640 | 0.68 | HTR1A (0.40) | LMNA | |
| SCHEMBL20157162 | 0.67 | BRPF1 (0.39) | BRPF1BRD4MEN1GAAKMT2A | |
| SCHEMBL2459075 | 0.66 | NCF1 (0.49) | BRPF1BRD4BIRC2ALDH1A1LMNA | |
| SCHEMBL2459077 | 0.66 | NCF1 (0.49) | BRPF1BRD4BIRC2ALDH1A1LMNA | |
| SCHEMBL20157167 | 0.65 | HTR1A (0.43) | LMNA | |
| SCHEMBL5745220 | 0.65 | BRPF1 (0.47) | BRPF1BRD4BIRC2GAAALDH1A1 | |
| SCHEMBL5745275 | 0.64 | BRPF1 (0.53) | BRPF1BRD4BIRC2XIAPMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |