SCHEMBL20140756

SCHEMBL20140756

FC(F)(F)c1ccc([PH](c2ccc(C(F)(F)F)cc2)(c2ccc(C(F)(F)F)cc2)c2ccc(C(F)(F)F)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.48
TSHR P16473 1/20 0.48
KIF11 P52732 6/20 0.46
TRPV6 Q9H1D0 2/20 0.44
CES2 O00748 1/20 0.44
CES1 P23141 1/20 0.44
ORAI1 Q96D31 1/20 0.44
ORAI2 Q96SN7 1/20 0.44
ORAI3 Q9BRQ5 1/20 0.44
MGLL Q99685 1/20 0.44
TAAR1 Q96RJ0 1/20 0.41
EPHX2 P34913 1/20 0.39
HTR3E A5X5Y0 1/20 0.39
HTR3B O95264 1/20 0.39
PLAU P00749 1/20 0.39
HTR3A P46098 1/20 0.39
HTR3D Q70Z44 1/20 0.39
HTR3C Q8WXA8 1/20 0.39
IDO1 P14902 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19434332 0.90 ALDH1A1 (0.59) ALDH1A1TSHRKIF11TRPV6CES2
SCHEMBL20408406 0.88 TSHR (0.42) ALDH1A1TSHRKIF11TRPV6CES2
SCHEMBL63468 0.80 ALDH1A1 (0.67) ALDH1A1TSHRKIF11TRPV6CES2
SCHEMBL6803143 0.80 KIF11 (0.48) ALDH1A1TSHRKIF11TRPV6CES2
SCHEMBL9546518 0.76 CES2 (0.43) ALDH1A1TSHRKIF11TRPV6CES2
SCHEMBL21724856 0.74 ALDH1A1 (0.40) ALDH1A1TSHRKIF11TRPV6CES2
Iodide SCHEMBL29093539 0.74 ALDH1A1 (0.59) ALDH1A1TSHRKIF11TRPV6CES2
Bromide SCHEMBL29093544 0.74 ALDH1A1 (0.59) ALDH1A1TSHRKIF11TRPV6CES2
SCHEMBL197238 0.71 KIF11 (0.78) ALDH1A1TSHRKIF11TRPV6CES2
SCHEMBL13410633 0.71 KIF11 (0.78) ALDH1A1TSHRKIF11TRPV6CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3475995-B1 QUANTUM DOT LIGHT EMITTING DEVICES DOW GLOBAL TECHNOLOGIES LLC (US) 2022-12-21 EP disclosed
US-20210210691-A1 POLYMERIC LAYER AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME. DOW GLOBAL TECHNOLOGIES LLC (US) 2021-07-08 US disclosed
US-10818860-B2 Quantum dot light emitting devices ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2020-10-27 US disclosed
US-20200066993-A1 POLYMERIC CHARGE TRANSFER LAYER AND ORGANIC ELECTRONIC DEVICE COMPRISING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2020-02-27 US disclosed
US-20190334106-A1 QUANTUM DOT LIGHT EMITTING DEVICES U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2019-10-31 US disclosed
US-10454036-B2 Polymeric charge transfer layer and organic electronic device containing the same DOW GLOBAL TECHNOLOGIES LLC (US) 2019-10-22 US disclosed
US-20180226584-A1 POLYMERIC CHARGE TRANSFER LAYER AND ORGANIC ELECTRONIC DEVICE CONTAINING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2018-08-09 US disclosed
US-20180212180-A1 POLYMERIC CHARGE TRANSFER LAYER AND ORGANIC ELECTRONIC DEVICE CONTAINING SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2018-07-26 US disclosed
WO-2018089181-A1 ORGANIC INDOLYL TRIARYLAMINE COMPOUNDS AND ELECTRONIC DEVICES COMPRISING AN ORGANIC LAYER CONTAINING SUCH COMPOUNDS DOW GLOBAL TECHNOLOGIES LLC (US) 2018-05-17 WO disclosed
WO-2018089181-A1 ORGANIC INDOLYL TRIARYLAMINE COMPOUNDS AND ELECTRONIC DEVICES COMPRISING AN ORGANIC LAYER CONTAINING SUCH COMPOUNDS DOW GLOBAL TECHNOLOGIES LLC (US) 2018-05-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10454036-B2 Polymeric charge transfer layer and organic electronic device containing the same CLTB, CYBA, L1CAM ALDH1A1 1599/4885TSHR 4851/4885KIF11 3448/4885
US-20180226584-A1 POLYMERIC CHARGE TRANSFER LAYER AND ORGANIC ELECTRONIC DEVICE CONTAINING THE SAME CLTB, CYBA, L1CAM ALDH1A1 1599/4885TSHR 4851/4885KIF11 3448/4885
US-20180212180-A1 POLYMERIC CHARGE TRANSFER LAYER AND ORGANIC ELECTRONIC DEVICE CONTAINING SAME CLTB, CYBA, EPCAM ALDH1A1 2925/4885TSHR 4855/4885KIF11 2870/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.