Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.43 |
| ▸ | KIF11 | P52732 | 4/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | PDE2A | O00408 | 2/20 | 0.33 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.32 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.32 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.32 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140756 | 0.76 | ALDH1A1 (0.48) | CES2KIF11IDO1ALDH1A1TSHR | |
| SCHEMBL6061078 | 0.69 | CES2 (0.56) | CES2KIF11PDE2APTPN5ALDH1A1 | |
| SCHEMBL19434332 | 0.69 | ALDH1A1 (0.59) | CES2KIF11ALDH1A1TSHRCES1 | |
| SCHEMBL20408406 | 0.67 | TSHR (0.42) | CES2KIF11ALDH1A1TSHRCES1 | |
| SCHEMBL24793381 | 0.66 | CES2 (0.52) | CES2KIF11PDE2APTPN5ALDH1A1 | |
| SCHEMBL1538943 | 0.66 | PDE2A (0.56) | CES2KIF11PDE2APTPN5TSHR | |
| SCHEMBL5841906 | 0.66 | CES2 (0.57) | CES2KIF11PDE2APTPN5ALDH1A1 | |
| SCHEMBL7601744 | 0.66 | CES2 (0.52) | CES2KIF11IDO1PDE2A | |
| SCHEMBL63468 | 0.65 | ALDH1A1 (0.67) | CES2KIF11IDO1ALDH1A1TSHR | |
| SCHEMBL6803143 | 0.65 | KIF11 (0.48) | CES2KIF11ALDH1A1TSHRCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993024600-A1 | OXIDATION-RESISTANT CYCLOPHOSPHAZENE FLUID INCLUDING TRIARYLPHOSPHINE OR PHOSPHINE OXIDE | THE DOW CHEMICAL COMPANY (US) | 1993-12-09 | — | — | WO | disclosed |