Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | P2RY12 | Q9H244 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20141002 | 0.82 | MCL1 (0.46) | MAPTGAATP53ALDH1A1KDM4E | |
| SCHEMBL20140646 | 0.80 | LMNA (0.42) | MAPTGAAALDH1A1KDM4ELMNA | |
| SCHEMBL20140521 | 0.76 | ALDH1A1 (0.44) | MAPTTSHRALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL20140827 | 0.75 | MTOR (0.51) | MAPTGAAALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL20139906 | 0.75 | POLB (0.47) | MAPTGAATSHRALDH1A1KDM4E | |
| SCHEMBL20140839 | 0.73 | POLB (0.46) | MAPTALDH1A1KDM4EL3MBTL1LMNA | |
| SCHEMBL20140882 | 0.73 | PKM (0.47) | MAPTGAATSHRALDH1A1KDM4E | |
| SCHEMBL20139954 | 0.73 | POLB (0.45) | MAPTGAATSHRALDH1A1KDM4E | |
| SCHEMBL5776077 | 0.72 | GFER (0.45) | MAPTALDH1A1KDM4EL3MBTL1LMNA | |
| SCHEMBL20139936 | 0.72 | MTOR (0.46) | GAAALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |