Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.36 |
| ▸ | COMT | P21964 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2015220 | 0.83 | CCR1 (0.39) | L3MBTL1ALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL2017454 | 0.82 | L3MBTL1 (0.41) | L3MBTL1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL29869804 | 0.68 | MEN1 (0.41) | L3MBTL1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL2015831 | 0.67 | L3MBTL1 (0.60) | L3MBTL1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL1812108 | 0.64 | ALDH1A1 (0.45) | L3MBTL1KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL1715894 | 0.64 | ALDH1A1 (0.38) | L3MBTL1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL2018364 | 0.63 | KDM4E (0.39) | L3MBTL1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL7689814 | 0.63 | COMT (0.57) | L3MBTL1KDM4EALDH1A1MEN1KMT2A | |
| Acetic Acid SCHEMBL29276419 | 0.63 | NAPRT (0.46) | L3MBTL1KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL2892496 | 0.63 | KDM4E (0.43) | L3MBTL1KDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011075630-A1 | SUBSTITUTED FUSED ARYL AND HETEROARYL DERIVATIVES AS PI3K INHIBITORS | INCYTE CORPORATION (US) | 2011-06-23 | — | — | WO | disclosed |