Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | CCR8 | P51685 | 1/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | COMT | P21964 | 1/20 | 0.33 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.33 |
| ▸ | IL1B | P01584 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2014276 | 0.83 | L3MBTL1 (0.41) | ALDH1A1MEN1KMT2ANPC1L3MBTL1 | |
| SCHEMBL2017454 | 0.83 | L3MBTL1 (0.41) | CCR1CCR8ALDH1A1SLC6A2HTT | |
| SCHEMBL22116608 | 0.76 | CCR1 (0.46) | CCR1CCR8ALDH1A1SLC6A2HTT | |
| SCHEMBL2013978 | 0.66 | HTT (0.50) | CCR1CCR8ALDH1A1SLC6A2HTT | |
| SCHEMBL1715894 | 0.65 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2AL3MBTL1BRD4 | |
| SCHEMBL22116718 | 0.64 | HSP90AA1 (0.52) | CCR1CCR8ALDH1A1SLC6A2HTT | |
| SCHEMBL2892994 | 0.64 | PSMD14 (0.43) | CCR1CCR8SLC6A2HTTCYP1A2 | |
| SCHEMBL29496114 | 0.63 | P2RX7 (0.61) | ALDH1A1KMT2ANPC1L3MBTL1P2RX7 | |
| SCHEMBL70978 | 0.63 | P2RX7 (0.61) | ALDH1A1KMT2ANPC1L3MBTL1P2RX7 | |
| Acetic Acid SCHEMBL29145357 | 0.63 | P2RX7 (0.47) | ALDH1A1HTTCYP1A2KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011075630-A1 | SUBSTITUTED FUSED ARYL AND HETEROARYL DERIVATIVES AS PI3K INHIBITORS | INCYTE CORPORATION (US) | 2011-06-23 | — | — | WO | disclosed |