Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | MMP14 | P50281 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2015220 | 0.83 | CCR1 (0.39) | L3MBTL1ALDH1A1HSP90AA1MEN1KMT2A | |
| SCHEMBL2014276 | 0.82 | L3MBTL1 (0.41) | L3MBTL1ALOX12KDM4EALDH1A1TDP1 | |
| SCHEMBL2018364 | 0.80 | KDM4E (0.39) | L3MBTL1ALOX12KDM4EALDH1A1CYP3A4 | |
| SCHEMBL7302758 | 0.75 | L3MBTL1 (0.46) | L3MBTL1ALOX12KDM4EALDH1A1CYP3A4 | |
| SCHEMBL29120017 | 0.72 | CCR1 (0.40) | L3MBTL1ALOX12KDM4EALDH1A1CYP3A4 | |
| SCHEMBL27790124 | 0.69 | ALOX12 (0.63) | L3MBTL1ALOX12KDM4ETDP1HSP90AA1 | |
| SCHEMBL2014457 | 0.67 | ALOX12 (0.64) | L3MBTL1ALOX12KDM4EALDH1A1CYP3A4 | |
| Chloroxine SCHEMBL4459987 | 0.65 | ALOX12 (0.81) | L3MBTL1ALOX12KDM4EALDH1A1CYP3A4 | |
| SCHEMBL365395 | 0.64 | ALDH1A1 (0.45) | L3MBTL1ALOX12KDM4EALDH1A1CYP3A4 | |
| SCHEMBL11694168 | 0.64 | KDM4E (0.64) | L3MBTL1ALOX12KDM4EALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011075630-A1 | SUBSTITUTED FUSED ARYL AND HETEROARYL DERIVATIVES AS PI3K INHIBITORS | INCYTE CORPORATION (US) | 2011-06-23 | — | — | WO | disclosed |