Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | NNMT | P40261 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30660353 | 0.83 | ALDH1A1 (0.38) | SIRT2SIRT1NNMTADORA2APOLB | |
| SCHEMBL5245987 | 0.78 | NNMT (0.41) | SIRT2SIRT1NNMTADORA2APOLB | |
| SCHEMBL30294896 | 0.78 | PDE10A (0.40) | SIRT2SIRT1NNMTPOLBTDP1 | |
| SCHEMBL5707601 | 0.78 | LOXL2 (0.39) | SIRT2SIRT1NNMTADORA2APOLB | |
| SCHEMBL15822496 | 0.78 | PDE10A (0.40) | SIRT2SIRT1NNMTPOLBTDP1 | |
| Hydrochloric Acid SCHEMBL7564938 | 0.77 | LOXL2 (0.38) | SIRT2SIRT1NNMTPOLBTDP1 | |
| SCHEMBL13180961 | 0.75 | NUDT1 (0.35) | SIRT2SIRT1NNMTADORA2APOLB | |
| SCHEMBL6935324 | 0.74 | NNMT (0.38) | SIRT2SIRT1NNMTADORA2APOLB | |
| SCHEMBL27517145 | 0.74 | NNMT (0.38) | SIRT2SIRT1NNMTADORA2APOLB | |
| SCHEMBL16364748 | 0.72 | SIRT2 (0.33) | SIRT2SIRT1NNMTADORA2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9969687-B2 | Compounds useful as CCR9 modulators | NORGINE B.V. (NL) | 2018-05-15 | — | — | US | disclosed |