Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 7/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.33 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14130426 | 0.90 | THRB (0.46) | THRBNPC1RAB9AMAPTPOLB | |
| SCHEMBL20153118 | 0.87 | THRB (0.41) | THRBNPC1RAB9AMAPTPOLB | |
| SCHEMBL20153095 | 0.83 | THRB (0.37) | THRBNPC1RAB9AMAPTPOLB | |
| SCHEMBL14130422 | 0.82 | THRB (0.46) | THRBNPC1MAPTGLO1TSHR | |
| SCHEMBL20148509 | 0.81 | POLB (0.36) | THRBNPC1RAB9AMAPTPOLB | |
| SCHEMBL13609834 | 0.81 | THRB (0.45) | THRBNPC1RAB9AMAPTPOLB | |
| SCHEMBL14130412 | 0.78 | TP53 (0.51) | RAB9AMAPTPOLBSMN1; SMN2TDP1 | |
| Scarlet Red SCHEMBL62339 | 0.73 | THRB (0.72) | THRBNPC1RAB9AMAPTPOLB | |
| Scarlet Red SCHEMBL6833437 | 0.73 | THRB (0.72) | THRBNPC1RAB9AMAPTPOLB | |
| Scarlet Red SCHEMBL1070583 | 0.73 | THRB (0.72) | THRBNPC1RAB9AMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10414903-B2 | Methods for synthesis of end-functionalized polyolefins | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2019-09-17 | — | — | US | disclosed |
| US-20180134873-A1 | METHODS FOR SYNTHESIS OF END-FUNCTIONALIZED POLYOLEFINS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2018-05-17 | — | — | US | disclosed |
| US-20180134873-A1 | METHODS FOR SYNTHESIS OF END-FUNCTIONALIZED POLYOLEFINS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2018-05-17 | — | — | US | disclosed |